Could a cotton swab in the nose take the sting out of migraine botox injections?
NCT ID NCT07571889
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This small study tests whether placing a cotton ball soaked in lidocaine (a numbing medicine) inside each nostril for 5 minutes before Botox injections reduces pain. 18 adults with chronic migraine who get regular Botox shots will receive both lidocaine and saline (salt water) on different days to compare. The goal is to see if this simple trick makes the injections more comfortable.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
lidocaine
What this could lead to
If it works, this could offer a simple, low-cost way to make Botox injections for migraine less painful.
What could go wrong
This is a very small pilot study with only 18 people, so results may not apply widely. The numbing effect might be minimal or no better than placebo.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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University Otolaryngology
RECRUITINGEast Providence, Rhode Island, 02905, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••