New pill taken every other day could prevent migraines

NCT ID NCT06409832

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether the drug rimegepant, taken as a tablet every other day, can help prevent migraines in adults who have at least four migraine days per month. Researchers will track changes in migraine frequency over three to twelve months. The goal is to see if rimegepant is effective and well-tolerated for long-term use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Rimegepant 75 mg orally disintegrating tablet

What this could lead to

If it works, this could provide a new, well-tolerated option for preventing migraines in people who have frequent attacks.

What could go wrong

This is an early-stage observational study with only 100 participants, so results may not apply to everyone. Rimegepant may not reduce migraine days for all users, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Headache Headache Disorders, Secondary migraine disorder migraine with aura migraine without aura Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • IRCCS National Neurological Institute "C. Mondino" Foundation

    RECRUITING

    Pavia, Pavia, 27100, Italy

    Contact Email: •••••@•••••

  • SOD Centro Cefalee e Farmacologia Clinica, AOU Careggi

    RECRUITING

    Florence, Florence, 50134, Italy

    Contact Email: •••••@•••••