No-Pill migraine fix? mayo clinic tests lifestyle training to cut headaches

NCT ID NCT05415020

Recruiting now Symptom relief Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study from Mayo Clinic tests whether a virtual lifestyle behavior training program can help people with chronic migraine have fewer attacks. Sixty adults with chronic migraine for at least one year will be randomly assigned to either the lifestyle program or a sham education session. The study will also look for biological markers that may predict who responds best to the program.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lifestyle behavior training
What this could lead to: If successful, this could lead to a drug-free behavioral program that helps people with chronic migraine have fewer attacks.
What could go wrong: This is a small, early-stage pilot study with only 60 participants. The sham comparison group also receives education, so the true benefit of the lifestyle protocol may be modest or unclear.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Headache headache disorder migraine disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC MIGRAINE HEADACHE HEADACHE DISORDERS LIFESTYLE FACTORS MIGRAINE MIGRAINE DISORDERS

No-Pill migraine fix? mayo clinic tests lifestyle training to cut headaches

Summary

What this could mean

Get notified about this study

Conditions

As listed by the trial registrant

Contacts and locations

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