CHRONIC KIDNEY DISEASES

This study looks at how well the HPV9 vaccine (Gardasil 9) works in people who have had a kidney or other solid organ transplant. Researchers will measure antibody levels in 30 adults aged 18-45 who are at least 6 months post-transplant and have not received this vaccine before. …

This study explores whether eating more fruits and vegetables can safely manage metabolic acidosis, a common complication of chronic kidney disease. The usual treatment, sodium bicarbonate, often causes side effects and doesn't always work. Researchers are testing if home-deliver…

This study looks at whether a natural substance called fisetin can help people with advanced chronic kidney disease. Researchers will measure changes in inflammation, stem cell health, and physical frailty after 14 days of treatment. The study involves 30 adults aged 40-80 with m…

This study looks at whether a combination of nurse health coaching, doctor training, and subsidies for a kidney-protecting drug can help slow the worsening of chronic kidney disease. About 724 adults with moderate-to-severe kidney disease in Singapore will be randomly assigned to…

This study looks at whether taking cinnamon supplements can reduce inflammation and oxidative stress in people with chronic kidney disease (CKD). It also checks if cinnamon can improve gut health. The study involves 30 adults with CKD who are either on dialysis or have moderate t…

This study tests a procedure called renal denervation, which uses a device to calm overactive nerves in the kidneys that can raise blood pressure. About 1,900 adults with uncontrolled high blood pressure will receive the treatment and be followed for years to see if it safely and…

This early-phase study tests whether the drug belumosudil can help people who receive a kidney transplant along with a stem cell transplant from the same donor. The goal is to see if it is safe and allows patients to stop taking most anti-rejection medicines over time. Sixteen ad…

This study looks at whether eating Brazil nuts can lower inflammation and oxidative stress in people with chronic kidney disease (stages 3-4). Researchers will measure changes in blood and gut bacteria markers. 50 patients from a kidney nutrition clinic are taking part.

This study tests a new ultrasound method to create detailed images of blood vessels in the kidneys. It includes healthy volunteers and people with chronic kidney disease who need a biopsy. The goal is to see if this imaging can help diagnose kidney disease without invasive proced…

This study tests a virtual health platform that provides exercise, nutrition, and psychological support for people on hemodialysis. About 70 adults with end-stage kidney disease will use the platform to improve their walking ability and overall well-being. The goal is to make hea…

This study is collecting health and genetic information from 120,000 people with chronic diseases like pancreatitis, diabetes, and arthritis. Researchers will look at how genes, lifestyle, and other factors affect disease progression and treatment response. The goal is to find be…

This study tests a decision aid that gives people with chronic kidney disease clear information about pregnancy and contraception. About 70 participants will use the tool and then answer a survey to see if it helps them feel more prepared to make reproductive health decisions. Th…

This study follows about 793 people with chronic kidney disease who were part of an earlier program. Researchers want to see if support and guidance helped them talk to doctors and family about transplants, start evaluations, and find living donors. No new treatment is given; the…

This study is creating a large database of 5,000 people with chronic kidney disease (CKD) to learn more about how the disease progresses and how it is currently treated. Researchers will collect information on patient health, treatments, and outcomes like kidney failure or heart …

This study follows 600 people with and without chronic kidney disease (CKD) for up to four years to compare how often memory loss, confusion, and daily activity problems occur. Researchers will also look for risk factors that make thinking and memory worse in CKD patients. Partic…

This study explores whether a special type of MRI can give doctors a clearer picture of kidney health in people with chronic kidney disease (CKD). Researchers will scan about 486 adults with mild to moderate CKD and compare the MRI results with standard tests and kidney biopsies.…

This study was designed to improve how doctors predict fluid removal during automated peritoneal dialysis for people with kidney failure. Researchers planned to test different fill volumes, dwell times, and sugar concentrations in the dialysis fluid, using digital tools to analyz…

This study looks at muscle and fat in people with chronic kidney disease (CKD) compared to healthy volunteers. Researchers want to understand why muscle loss happens earlier and faster in CKD, so they can design better treatments in the future. About 80 adults with and without CK…

This study looks at how two drugs, Sacubitril/Valsartan (Entresto) and MANP, affect people with a type of heart failure called HFpEF, which also involves chronic kidney disease or shortness of breath during exercise. Researchers will measure changes in body chemicals and kidney f…

This study aimed to see if a computer program could predict how long patients would stay in a home hospital. Researchers planned to use past patient data to train the program, but the study was withdrawn before any participants were enrolled. No results are available.

This study collects information from about 1000 critically ill infants who need a special type of dialysis (blood cleaning) using a new machine called CARPEDIEM. The goal is to learn why doctors start this treatment, how to best use it, and what happens to the babies afterward. T…

This study screened over 16,600 adults aged 45-70 with at least one risk factor (like high blood pressure or smoking) but no known heart disease. Researchers used ultrasound and urine tests to find hidden signs of artery hardening and kidney damage. The goal is to learn what fact…

This study looks at whether adding geriatric care to regular dialysis treatment helps older patients manage common problems like depression, memory trouble, falls, and medication issues. About 120 dialysis patients aged 55 and older will take part. The goal is to see if this appr…

This study aimed to see if a computer program could predict potassium levels in the blood using a simple heart monitor (single-lead ECG) and patient data. It was designed for adults in a home hospital program with conditions like heart failure or kidney disease. However, the stud…

This study explores whether low levels of pyrophosphate, a natural substance that prevents hardening, can predict artery calcification in people with moderate chronic kidney disease. Researchers will measure pyrophosphate in 242 participants and track changes in artery calcificat…

This study uses advanced MRI techniques to measure changes in heart muscle tissue in 8,000 adults with various heart conditions. The goal is to see if these measurements can help doctors better detect disease and predict future health problems like heart failure or death. Partici…