CARDIAC ARREST (CA)

This study is testing a new medical device called NEURESCUE that aims to improve survival from cardiac arrest. The device is a special balloon placed in a major artery to quickly redirect more blood to the heart and brain during resuscitation efforts. Researchers will compare sta…

This study is testing a new, standardized approach to giving breaths during CPR for children who suffer cardiac arrest in the hospital. It aims to see if this method helps more children survive and leave the hospital with good brain function. The research will involve over 1,500 …

This study is testing if adding a gentle, constant pressure to the lungs during CPR (called PEEP) helps restart the heart and improves survival for adults who suffer a cardiac arrest outside the hospital. Researchers will compare standard CPR to CPR with this added pressure to se…

This study is testing if starting a special advanced life support machine (called ECMO) right at the scene of a cardiac arrest is better than waiting until the patient reaches the hospital. It will compare survival and brain recovery in 90 patients. The main goal is to see if get…

This study is testing a new, faster type of CT scan to quickly check for blocked heart arteries in people who have survived a cardiac arrest. The goal is to see if this scan is as accurate as the current, more complex test (coronary angiography) at finding blockages. If it works,…

This study is testing a portable MRI machine that can be brought to a patient's bedside to look for brain injury after their heart stops. Researchers want to see if this portable scanner works as well as traditional MRI machines at detecting injury, and if it can track how the in…

This study is testing two different mind-body programs designed to help cardiac arrest survivors and their caregivers manage emotional distress like anxiety and depression. The programs involve weekly sessions that teach mindfulness and resilience skills, starting in the hospital…

This study is testing whether a new mixed reality CPR training system works as well as standard instructor-led classes. Researchers will enroll 120 adults who haven't had recent CPR training and randomly assign them to either the new virtual training or traditional classes. The m…

This study aims to learn what helps people recover best after serious heart events like heart attacks, surgery, or heart failure. Researchers will observe 10,000 patients during their cardiac rehabilitation program, collecting health data over many years. The goal is to find patt…

This study aims to improve how doctors predict brain recovery in patients who survive a cardiac arrest. Researchers will test 50 patients using a special blood analysis and a bedside brain ultrasound to look for early signs of brain injury. The goal is to create better tools to h…

This study aims to understand why brain damage worsens in the days after a person's heart stops. Researchers will analyze spinal fluid from 60 patients who survived a cardiac arrest to look for biological clues linked to poor recovery. The goal is to discover potential targets fo…

This study aims to understand how the quality of breathing support given during CPR affects short-term survival after a person's heart stops in the hospital. Researchers will observe 900 adult patients to see if specific breathing rates and volumes during resuscitation are linked…

This study aims to track the long-term health of cardiac arrest survivors for five years after they received an experimental treatment. The treatment involved rapidly cooling the body to protect the brain and heart from damage after the heart was restarted. Researchers will follo…

This study looks at breathing data collected from about 150 people who suffered cardiac arrest outside the hospital. Researchers want to understand if a measurement called the Airway Opening Index (AOI), taken from a breathing monitor, is common during CPR and if it can help pred…

This study aims to identify early signs that predict when unconscious cardiac arrest patients will successfully wake up after sedation. Researchers will observe 250 patients using non-invasive brain monitoring tools like pupil measurements and brain wave tests during their ICU st…