CARDIAC ARREST (CA)

This study tests whether an external abdominal tourniquet can temporarily block blood flow to the lower body during cardiac arrest, redirecting it to the brain and heart. Researchers will try it on 5 adults with non-traumatic cardiac arrest outside a hospital. The goal is to see …

This study tests whether using special devices to precisely control breathing during CPR can help more people survive a cardiac arrest. About 852 adults who have a cardiac arrest in the hospital will be randomly assigned to either standard manual breathing help or breathing tailo…

This study tests whether moving cardiac arrest survivors to a specialized hospital improves their recovery. About 1,600 adults who were revived after an out-of-hospital cardiac arrest will be randomly assigned to either stay at the nearest hospital or be transferred to a specialt…

This study tests a new CPR method called Bio-CPR, which synchronizes chest compressions with ventilation using a machine. Researchers will compare it to standard CPR in 408 adults who have a witnessed cardiac arrest. The goal is to see if this coordinated approach improves breath…

This study examines whether volunteers alerted by a smartphone app can improve survival for people who have a cardiac arrest outside the hospital. Researchers will compare outcomes for about 5,200 adults who either did or did not receive help from these first responders. The goal…

This study looks at 100 adults who needed a breathing machine after a heart attack or cardiac arrest. Researchers want to see how often acid-base problems happen and compare the settings doctors used with those suggested by a computer algorithm. The goal is to improve future care…

This study tests a drug called GC7 in 20 people who have had a cardiac arrest and been revived. The goal is to see if GC7 can reduce cell damage caused by the sudden return of blood and oxygen. Researchers will measure stress levels in blood cells and look for signs of improved r…

This study looks at how often colon damage (ischemia) happens in people who survive cardiac arrest and receive CPR. Researchers will perform a bedside colonoscopy 24-36 hours after CPR to check for colon injury. The goal is to better understand this complication and improve care …

This study will collect information from 1,200 patients in the French West Indies and Guiana who received ECMO, a machine that helps the heart and lungs. Researchers aim to track survival rates and complications to better understand how ECMO works in this region. The study does n…

This observational study tests a new bedside device that measures nucleosome levels in the blood of critically ill ICU patients. Researchers want to see if these levels can predict which patients are likely to die within 30 days. The study will enroll 130 adults with conditions l…

This study compares a standard high-field MRI with a portable low-field MRI to see if the portable version can detect brain damage in people in a coma after cardiac arrest. Researchers will scan 60 participants (30 coma patients and 30 healthy volunteers) multiple times over two …