Blood test may forecast brain recovery after cardiac arrest
NCT ID NCT07760636
First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time
Summary
This study investigates whether levels of a protein called neurofilament light chain (NFL) in the blood can predict neurological recovery in people who remain comatose after a cardiac arrest. Researchers will measure NFL at several time points over the first week in the ICU and compare these levels with patients' eventual neurological outcomes, ranging from full recovery to severe disability or death. The goal is to see if NFL could serve as a reliable early marker to help guide treatment decisions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Measurement of neurofilament light chain (NFL) levels in blood at multiple time points after ICU admission
- What this could lead to
- If NFL levels reliably predict outcomes, doctors could better identify which patients may recover and guide care decisions after cardiac arrest.
- What could go wrong
- This is an observational study, so it cannot prove cause and effect. NFL levels may not be accurate enough to replace current prognostic methods, and results may vary across different patient groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Medical ICU
Paris, IDF, 75014, France
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Other studies related to the condition(s) this trial covers.
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