A simple bedside test may predict brain damage after cardiac arrest

NCT ID NCT06776302

Completed Knowledge-focused Sponsor: University Medical Centre Maribor Source: ClinicalTrials.gov ↗

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This trial investigates whether two simple, non-invasive tests can detect changes in brain oxygen levels in unconscious patients who have survived a cardiac arrest. The tests involve a controlled infusion of a blood-pressure-raising drug and a passive leg raise to increase blood flow to the brain. Researchers aim to see if these oxygen changes match other established methods for assessing neurological damage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: norepinephrine infusion and passive leg raise
What this could lead to: If successful, this approach could offer a simple, bedside way to assess brain damage in unconscious patients after cardiac arrest.
What could go wrong: This is a very small, early-stage study with only 20 participants. The tests are not used to guide treatment, and results may not translate to better outcomes.

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Conditions

The condition(s) this trial relates to.

cardiac arrest

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC ARREST (CA)

Contacts and locations

Locations

University clinical center Maribor

Maribor, 2000, Slovenia

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Other studies related to the condition(s) this trial covers.