Can a High-Tech CPR bundle boost heart restart rates?
NCT ID NCT07754656
First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time
Summary
This trial tests whether an adapted CPR bundle can increase the chance of restarting the heart in adults who suffer cardiac arrest outside a hospital. Participants are randomly assigned to receive either standard advanced life support or a modified approach that includes mechanical chest compressions, head-up positioning, an impedance threshold device, continuous epinephrine infusion, and double defibrillation. The main question is whether this bundle leads to a higher rate of return of spontaneous circulation compared to standard care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Adapted CPR bundle including mechanical chest compressions, head-up CPR, impedance threshold device, arterial line, continuous epinephrine infusion, and double sequence defibrillation
- What this could lead to
- If successful, this could point toward a more effective CPR approach that improves survival from cardiac arrest.
- What could go wrong
- This is a single-center trial with 216 participants, so results may not apply broadly. The intervention is complex and may not improve outcomes over standard care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Kepler University Hospital
RECRUITINGLinz, Upper Austria, 4020, Austria
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