AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
Clinical trials for AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE explained in plain language.
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Parkinson's drug repurposed to fight kidney disease?
Disease control Recruiting nowThis study tests whether a rotigotine skin patch, a drug used for Parkinson's disease, is safe for people with autosomal dominant polycystic kidney disease (ADPKD). ADPKD causes fluid-filled cysts in the kidneys and can lead to kidney failure. The trial will give 120 adults eithe…
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
Phase: PHASE2 • Sponsor: University Hospital, Rouen • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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New drug aims to shrink cysts in genetic kidney disease
Disease control Recruiting nowThis study tests an investigational drug called ABBV-CLS-628 in adults with autosomal dominant polycystic kidney disease (ADPKD), a genetic condition that causes fluid-filled cysts to grow in the kidneys. About 240 participants worldwide will receive either the drug or a placebo …
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
Phase: PHASE2 • Sponsor: Calico Life Sciences LLC • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Keto diet tested as a way to delay kidney failure
Disease control Recruiting nowThis study looks at whether a well-formulated ketogenic diet can delay the progression of polycystic kidney disease in 20 adults who are at high risk for kidney failure. Participants will follow the diet for one year and have regular blood tests, urine tests, and MRI scans to tra…
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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New drug AZD1613 tested for safety in kidney disease patients
Disease control Recruiting nowThis early-stage study tests the safety of a new drug called AZD1613 in 40 adults with autosomal dominant polycystic kidney disease (ADPKD), a condition that causes kidney cysts. Participants receive either the drug or a placebo to check for side effects and how the drug moves th…
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
Phase: PHASE1 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Diabetes drug metformin tested as new weapon against kidney disease
Disease control Recruiting nowThis study tests whether metformin, a drug used for diabetes, can slow the loss of kidney function in people with early-stage autosomal dominant polycystic kidney disease (ADPKD). About 1,174 adults aged 18-70 with mild to moderate kidney decline will take metformin or a placebo …
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
Phase: PHASE3 • Sponsor: The University of Queensland • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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New study seeks clues to kidney disease in young adults
Knowledge-focused Recruiting nowThis study aims to understand how oxidative stress and the body's antioxidant defenses work in early stages of autosomal dominant polycystic kidney disease (ADPKD). Researchers will measure various biomarkers in blood and urine, and use MRI to measure kidney size. The goal is to …
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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New biomarker study aims to track kidney disease severity
Knowledge-focused Recruiting nowThis study is looking for markers in urine and blood that can show how severe autosomal dominant polycystic kidney disease (ADPKD) is in its early stages. Researchers will measure NOX4, mitochondrial DNA, and other substances in 60 people aged 15-40 with early ADPKD. The goal is …
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Massive PKD data collection aims to unlock secrets of kidney disease
Knowledge-focused Recruiting nowThis study is building a large database of health information from people with autosomal dominant polycystic kidney disease (PKD), the most common inherited kidney disease. Researchers will collect data from 1,000 adults over time to better understand complications like high bloo…
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
Sponsor: The Rogosin Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Diabetes drug empagliflozin studied for kidney disease mineral effects
Knowledge-focused Recruiting nowThis phase 2 trial is testing whether the diabetes drug empagliflozin changes how the kidneys handle calcium, phosphate, and magnesium in people with autosomal dominant polycystic kidney disease (ADPKD). Forty adults will take either empagliflozin or a placebo for two weeks, then…
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
Phase: PHASE2 • Sponsor: Cantonal Hospital Graubuenden • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:19 UTC
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New registry aims to speed up PKD research
Knowledge-focused Recruiting nowThis study is creating a registry and biobank of 350 adults with autosomal dominant polycystic kidney disease (ADPKD) in the Mid-Atlantic region. Participants will provide medical information, have kidney volume measured by MRI, and donate blood, urine, and DNA samples. The goal …
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:39 UTC