AGE RELATED MACULAR DEGENERATION

This study tested whether a pre-filled syringe of the medicine SB11 (a biosimilar to ranibizumab) is easy for eye doctors to use. Thirty adults with wet age-related macular degeneration, macular edema from retinal vein occlusion, or myopic choroidal neovascularization received on…

This study tested an experimental drug called ALK-001 in people with geographic atrophy, an advanced form of dry age-related macular degeneration that causes blind spots. About 200 participants received the drug and 100 received a placebo. The goal was to see if ALK-001 could slo…

This study tested whether the antibiotic minocycline, taken as a pill twice daily for at least 3 years, could safely slow the growth of geographic atrophy—an advanced form of age-related macular degeneration that causes blind spots. Thirty-seven adults aged 55 and older with geog…

This study looked at two different schedules of the drug brolucizumab for people with wet age-related macular degeneration (AMD), a condition that causes vision loss. Fifty-two adults who had already received treatment for AMD took part. The goal was to see which dosing plan work…

This study checks the long-term safety of an eye injection called avacincaptad pegol for people with geographic atrophy, a form of advanced age-related macular degeneration that causes vision loss. About 278 adults who finished a previous study of this drug will receive the injec…

This study tested a drug normally used for Parkinson's disease (carbidopa-levodopa) in 35 people with wet age-related macular degeneration (AMD). The goal was to see if it could improve vision and reduce the need for regular eye injections. Participants took the drug by mouth whi…

This study tested whether a drug used for Parkinson's disease (carbidopa-levodopa) could help people with wet age-related macular degeneration (AMD), a leading cause of vision loss. Twenty participants who had not yet received standard treatment took the drug for a short time. Re…

This study tested a robotic arm that holds a tiny needle steady during eye surgery for people with bleeding under the retina caused by age-related macular degeneration. The robot helped surgeons inject a clot-busting drug (tPA) precisely under the retina. The main goal was to see…

This study tested whether regular eye injections of a drug called aflibercept could prevent the 'wet' form of age-related macular degeneration (AMD) in people whose other eye already had it. 128 high-risk participants received either the drug or a sham injection. The main goal wa…

This study tested whether a steroid eye drop called loteprednol can reduce pain after routine eye injections for age-related macular degeneration. 64 patients received either loteprednol or artificial tears after their injection and rated their pain over one week. The goal is to …

This study looked at 68 adults with wet age-related macular degeneration (AMD) to see if a newer type of eye scan (OCT angiography) changes when doctors give injections compared to the standard scan (OCT B-scan). The goal was to find out if the newer scan helps keep vision stable…

This study looked at how vision changes over time in 60 people with geographic atrophy, an advanced form of dry age-related macular degeneration that causes permanent vision loss. Researchers used past medical records and eye scans to see which features of the retina are linked t…

This study looked at the best ways to find eye diseases like cataracts, glaucoma, and diabetes-related vision loss in communities. Over 87,000 people aged 50 and older in Nepal took part. Communities were randomly assigned to one of four approaches: a full eye screening program, …

This study followed 57 people with age-related macular degeneration (AMD) for up to 5 years to see how their eyes adjust to darkness. Participants had yearly eye exams and dark adaptation tests, where they sat in a dark room and pressed a button when they saw a light. The goal wa…

This study looked at whether telling healthy adults their genetic risk for age-related macular degeneration (AMD) encourages them to eat more carotenoid-rich foods, which are good for eye health. Eighty Caucasian participants aged 18 to 64 without AMD were given genetic risk info…

This study tested whether an AI tool helps eye doctors diagnose four common eye diseases—diabetic retinopathy, age-related macular degeneration, retinal vein occlusion, and glaucoma—more accurately and quickly. Ten eye doctors at five hospitals read eye images with and without AI…

This study gathered eye scans from 1,000 people with intermediate age-related macular degeneration (AMD) to find patterns that predict if the disease will get worse. Researchers analyzed images taken over two years to see which eyes developed new or larger areas of damage. The go…

This study looked at 100 people with wet age-related macular degeneration (AMD) to measure certain proteins in their eye fluid. The goal was to find out why about 37% of patients do not respond well to standard anti-VEGF injections. Researchers measured levels of proteins that pr…

This study looked at 470 people with age-related macular degeneration (AMD) to see if special eye scans (SDOCT) can predict who will lose vision or develop advanced disease. Researchers tracked changes in the retina over time to find early warning signs. The goal is to better und…

This study looked at 556 people to understand why those with early age-related macular degeneration (AMD) have trouble seeing in the dark. Researchers used advanced eye imaging to map how changes in the retina affect night vision recovery. The goal was to find reliable markers fo…

This study followed 26 adults aged 55 and older with early age-related macular degeneration (AMD) or healthy eyes for up to 5 years. Researchers used eye exams, imaging, and vision tests to track changes in the retina and how they relate to vision loss. The goal was to better und…

This study looked at whether a simple test measuring how fast eyes recover in the dark can help track early to middle dry age-related macular degeneration (AMD). Researchers followed 217 adults aged 50 and older, with or without AMD, for up to 5 years. The goal was to see if chan…

This study followed 20 adults aged 55 and older with geographic atrophy, an advanced form of age-related macular degeneration that causes central vision loss. Researchers measured how the damaged area in the eye changed over nearly 4 years using eye exams and photos. The goal was…

This study looked at whether giving people with age-related macular degeneration (AMD) personalized risk information—including genetic testing—along with coaching, helps them make lasting lifestyle changes. 150 participants with early or intermediate AMD were followed to see if t…

This study followed 516 elderly French people for up to 8 years to see how many develop age-related macular degeneration (AMD), a leading cause of blindness. Researchers looked at genetic, clinical, and lifestyle factors that might increase risk. The goal is to better understand …