New dosing strategy tested for common eye disease

NCT ID NCT04679935

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 31 times

Summary

This study tested two different schedules of the eye injection brolucizumab in 52 adults with wet age-related macular degeneration (AMD) whose vision was not fully controlled by previous treatment. The goal was to see which dosing plan works better and is safer over 52 weeks. Participants received the same drug but at different intervals, and researchers measured changes in vision and treatment needs.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Regensburg, Bavaria, 93053, Germany

  • Novartis Investigative Site

    Frankfurt am Main, Hesse, 60549, Germany

  • Novartis Investigative Site

    Berlin, 13353, Germany

  • Novartis Investigative Site

    Bonn, 53105, Germany

  • Novartis Investigative Site

    Düsseldorf, 40225, Germany

  • Novartis Investigative Site

    Göttingen, 37075, Germany

  • Novartis Investigative Site

    Hanover, 30625, Germany

  • Novartis Investigative Site

    Homburg, 66421, Germany

  • Novartis Investigative Site

    Leipzig, 04103, Germany

  • Novartis Investigative Site

    Lübeck, 23538, Germany

  • Novartis Investigative Site

    Magdeburg, 39120, Germany

  • Novartis Investigative Site

    Mainz, 55131, Germany

  • Novartis Investigative Site

    Marburg, 35039, Germany

  • Novartis Investigative Site

    Münster, 48149, Germany

  • Novartis Investigative Site

    Neubrandenburg, 17036, Germany

  • Novartis Investigative Site

    Ulm, 89075, Germany

  • Novartis Investigative Site

    Lausanne, CHE, 1000, Switzerland

  • Novartis Investigative Site

    Bern, 3007, Switzerland

  • Novartis Investigative Site

    Zurich, 8063, Switzerland

Conditions

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