Swine influenza

This study tested an inactivated H1N1 flu vaccine in 122 kidney transplant recipients who were at least 6 months post-transplant and on triple immunosuppression. The goal was to see if the vaccine could safely trigger an immune response. Researchers measured antibody levels and t…

This phase 2 study tested a non-adjuvanted H1N1 flu vaccine in 110 pregnant women to see if it is safe and triggers a good immune response. Participants received two doses of the vaccine and were monitored for side effects. The goal is to protect both mothers and their babies fro…

This early-stage study tested a 'prime-boost' approach for a universal flu vaccine. Researchers gave an inactivated H5N1 flu shot to 32 healthy adults, some of whom had previously received other experimental flu vaccines. The goal was to see if this method could trigger broad imm…

This early-phase study tested a new oral drug called CC-42344 in 80 healthy adults to see if it is safe and how the body processes it. The drug is designed to stop the influenza A virus from multiplying. The study did not treat actual flu patients, but the results will help decid…

This study tested whether the antiviral drug Amizon (enisamium iodide) can help adults with colds or flu feel better faster. One hundred adults aged 18 to 60 took either Amizon or a placebo pill for 7 days, starting within a day of their first symptoms. Researchers tracked sympto…

This study tested a new flu medicine called ZSP1273 in 72 children aged 2 to 17 with influenza A. The goal was to see how safe it is, how the body processes it, and whether it helps reduce flu symptoms. The trial took place in China and has already been completed.

This study looked at whether giving hospital-level care to acutely ill adults in their own homes in rural areas works well. 160 people with various conditions like infections, heart failure, or COPD took part. The goal was to see if this approach could lower costs and help patien…

This study tested a new flu medicine called ADC189 in 190 children aged 2 to 11 with influenza. The medicine is given as a single dose, either as a tablet or granules. The goal was to see if it is safe and works well in younger children, who currently have limited treatment optio…

This study tested two new rapid tests that use a single nose swab to detect COVID-19, influenza A/B, and RSV. Researchers checked how accurate the tests are compared to standard lab methods and whether healthcare workers find them easy to use. The study involved 589 people with s…

This study collected nasal swabs, throat swabs, and saliva samples from 79 people with symptoms of flu, RSV, or COVID-19. The samples were used to help evaluate a point-of-care device called LumiraDx, which aims to quickly and accurately detect these viruses. The study focused on…

This study checked how well a new rapid test (LumiraDx) detects COVID-19 and flu A/B from a simple nose swab. Over 1,000 people with symptoms took part at clinics. The test aims to give fast results at the point of care, helping doctors tell these illnesses apart quickly.

This study looked at how well a new, quick finger-prick test (LumiraDx CRP) measures CRP levels compared to a standard lab test. CRP is a marker of infection, inflammation, or tissue injury. 79 adults with symptoms of these conditions took part. The goal was to see if the new tes…

This study checked how accurate two rapid tests (LumiraDx SARS-CoV-2 Ag Ultra and LumiraDx SARS-CoV-2 & Flu A/B) are at detecting COVID-19 and flu in people with symptoms. 716 participants provided nasal swabs at clinics. The results were compared to standard lab tests to measure…

This study tested a new rapid test (LumiraDx Influenza A/B + RSV Test) that uses a nasal swab to quickly detect flu A, flu B, and RSV. Over 500 people with cold or flu-like symptoms took part. The test was performed by healthcare workers at point-of-care sites and compared to sta…

This study tested whether giving general practitioners a rapid C-reactive protein (CRP) test helps them decide when antibiotics are truly needed for patients with respiratory infections. 140 patients with symptoms like cough, fever, or sore throat took part. Doctors in the test g…

This study tested a new rapid test that checks for flu A, flu B, COVID-19, and RSV using one nasal swab. Over 1,100 people with respiratory symptoms took part. The goal was to see how well the test works compared to standard lab tests.

This study checked how well a new rapid test (iHealth COVID-19/Flu A&B) can detect COVID-19 and flu A and B in people with respiratory symptoms. About 588 people with two or more symptoms provided nose swabs. The test's results were compared to a standard lab test to see how accu…

This early study tested whether a special PET scan using a radioactive form of vitamin B9 (11C-PABA) can help doctors see infections deep inside the body. Researchers scanned 13 healthy people and patients with known or suspected infections. The goal was to see if this method can…

This study looked at whether FebriDx, a rapid fingerstick test, can accurately tell bacterial from non-bacterial acute respiratory infections when used by people without lab training. Researchers compared results from untrained operators to trained ones in 800 patients with fever…

This study tested whether the dietary supplement MitoQ could prevent severe viral infections, like COVID-19, in adults who had close contact with a sick person. Eighty asymptomatic adults were given MitoQ or no treatment and monitored for illness. The goal was to see if the suppl…

This study tested the H1N1 flu vaccine in 439 people with cystic fibrosis to see if it prevents the flu and is safe. Participants included adults, children, pregnant women, and lung transplant recipients. Researchers measured immune response and tracked flu symptoms, using antivi…

This study looked at whether giving a low dose of a muscle relaxant (rocuronium) during bronchoscopy—a procedure where a tube is inserted into the lungs—could reduce complications like throat spasms and coughing. 153 adults having elective bronchoscopy were split into two groups:…

This study measured levels of mannose-binding lectin (MBL), a protein involved in immune response, in 97 ICU patients with severe H1N1-related acute respiratory distress syndrome (ARDS). Researchers wanted to see if higher or lower MBL levels were linked to a higher risk of death…

This study looked at 537 patients with respiratory infection symptoms to see how the types of viruses and bacteria changed from the COVID-19 pandemic period to after it. Researchers used a special PCR test to detect multiple germs at once. The goal was to understand how pandemic …

This study checked how accurate a new test (Xpert Expanded Respiratory Panel) is at finding respiratory infections. Researchers tested nose swabs from 3,200 people with symptoms and compared results to other tests. The goal was to see if the new test works well enough for routine…

This study tested whether adding infectious disease experts to primary care teams helps reduce unnecessary antibiotic use. Over 1,300 patients from six clinics in Spain took part. Doctors in the expert-advised group could call or meet with specialists to discuss tricky cases. The…

This study looked at how well the 2023 and 2024 flu vaccines protect against influenza A. Researchers gave the 2023 vaccine to 23 healthy adults between May and June 2024, when the vaccine was about to expire, to compare their immune responses with people who got the 2023 vaccine…

This study tested a program to help doctors prescribe antibiotics more appropriately for common childhood infections like earaches, sore throats, and sinusitis. Over 1,000 doctors took part, receiving online training, personalized feedback on their prescribing habits, and support…

This study reviewed records from 542 adults in 20 ICUs across China who had severe flu (Influenza A) and breathing failure. Researchers divided patients into those who also developed a fungal lung infection (aspergillosis) and those who did not, to understand risk factors and sur…

This study tested a computer tool that helps nurses decide when antibiotics are needed for common respiratory infections like colds and sore throats. The tool, built into the electronic health record, calculates a patient's risk and suggests appropriate care. Researchers measured…

This study followed 919 pregnant women in Paris to see how often they caught H1N1 flu during the 2009 pandemic and what happened to their pregnancies. Researchers also checked if the flu vaccine was safe. The goal was to better understand the risks of flu during pregnancy.

This study looked at 156 critically ill patients to find out what factors help achieve the right levels of beta-lactam antibiotics in the blood. Researchers collected clinical data and used therapeutic drug monitoring to see which patients reached target concentrations. The goal …

This study looked at 30 people in the ICU with severe H1N1 flu who needed a breathing machine. Researchers collected fluid from the lungs to study the virus and the body's immune response. The goal was to learn more about what causes severe illness, not to test a new treatment.

This study followed 38 adults who survived severe breathing failure from the 2009 H1N1 flu. Researchers compared those who needed a machine to oxygenate their blood (ECMO) with those who did not. They measured lung function, quality of life, and mental health at least 9 months af…

This completed study looked at how a special form of vitamin B3 (nicotinamide) is processed in 28 patients with low tryptophan levels due to respiratory infections or inflammatory bowel disease. Participants took either 500 mg or 1000 mg of the supplement daily for four weeks. Th…

This completed study looked at how 147 healthy hospital workers responded to the seasonal flu vaccine and the H1N1 pandemic vaccine. Researchers measured antibody and cellular immune responses, focusing on how age and previous flu vaccinations affected those responses. The goal w…