Flu shot study reveals how age and prior vaccines shape immunity

NCT ID NCT01063608

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study looked at how 147 healthy hospital workers responded to the seasonal flu vaccine and the H1N1 pandemic vaccine. Researchers measured antibody and cellular immune responses, focusing on how age and previous flu vaccinations affected those responses. The goal was to better understand immunity patterns to help guide public health vaccination strategies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Anti-H1N1v Vaccine (biological) and seasonal influenza vaccine

What this could lead to

If successful, this study could help public health officials better understand how age and past flu shots affect immune responses, potentially improving future vaccination strategies.

What could go wrong

This is a completed observational study, not a treatment trial. It measures immune markers, not clinical outcomes like preventing illness, so results may not directly change practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

swine influenza influenza prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre d'Investigations Cliniques (CIC), Hopital Cochin

    Paris, Île-de-France Region, 75014, France

  • Hopital Pitie Salpetriere

    Paris, Île-de-France Region, 75013, France