Flu shot study reveals how age and prior vaccines shape immunity

NCT ID NCT01063608

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study looked at how 147 healthy hospital workers responded to the seasonal flu vaccine and the H1N1 pandemic vaccine. Researchers measured antibody and cellular immune responses, focusing on how age and previous flu vaccinations affected those responses. The goal was to better understand immunity patterns to help guide public health vaccination strategies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Anti-H1N1v Vaccine (biological) and seasonal influenza vaccine
What this could lead to
If successful, this study could help public health officials better understand how age and past flu shots affect immune responses, potentially improving future vaccination strategies.
What could go wrong
This is a completed observational study, not a treatment trial. It measures immune markers, not clinical outcomes like preventing illness, so results may not directly change practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre d'Investigations Cliniques (CIC), Hopital Cochin

    Paris, Île-de-France Region, 75014, France

  • Hopital Pitie Salpetriere

    Paris, Île-de-France Region, 75013, France