Spastic diplegia
MONDO:0001167A type of cerebral palsy characterized by spasticity and hypertonia of the lower extremities bilaterally, particularly the legs, hips, and pelvis; this is the most common (70%) form of cerebral palsy.
Also known as: Little disease, Little's disease, diplegic infantile cerebral palsy, cerebral palsy spastic diplegic
58 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Trunk training may unlock better arm control in kids with cerebral palsy
Disease control CompletedThis trial tests whether intensive segmental trunk training (ISTT) can improve upper limb function and seated stability in children aged 4-12 with spastic diplegic cerebral palsy. Participants perform structured exercises targeting trunk control five times per week for eight week…
Phase: NA • Sponsor: University of Lahore • Aim: Disease control
Last updated Aug 01, 2026 00:00 UTC
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Botox shots help kids with cerebral palsy move better?
Disease control CompletedThis study looked at whether Botox injections, combined with physical therapy, can improve selective motor control (the ability to move one joint at a time) in children with spastic diplegia cerebral palsy. Forty children aged 4-12 received Botox in their spastic muscles plus 30 …
Phase: PHASE4 • Sponsor: Gaziosmanpasa Research and Education Hospital • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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Core stability exercises may boost sensory and motor skills in kids with cerebral palsy
Disease control CompletedThis study tests whether reflex-mediated core stability exercises can improve sensory processing and gross motor function in children with cerebral palsy. The trial includes children aged 4 to 12 with spastic diplegic CP. One group does reflex-based core exercises while the other…
Phase: NA • Sponsor: Riphah International University • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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New exercise method aims to help kids with cerebral palsy sit and stand better
Disease control CompletedThis study tests whether Cuevas Medek Exercises can improve posture and balance in children with spastic cerebral palsy. 54 children will be randomly assigned to either the new exercises or standard therapy. The goal is to see if these exercises help children control their body p…
Phase: NA • Sponsor: Riphah International University • Aim: Disease control
Last updated Jul 22, 2026 00:00 UTC
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Could swinging and trampoline jumps help children with cerebral palsy walk better?
Disease control CompletedThis trial investigates whether adding vestibular stimulation—activities like swinging, trampoline jumps, and balance exercises—to standard physiotherapy improves gross motor function and mobility in children aged 6 to 12 with spastic diplegic cerebral palsy. Participants receive…
Phase: NA • Sponsor: Ibadat International University, Islamabad • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
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New exercise program may help kids with cerebral palsy move better
Disease control CompletedThis study compares two physical therapy approaches—Dynamic Movement Intervention (DMI) and the Bobath method—in 58 children with spastic cerebral palsy. The goal is to see which therapy better improves motor skills, balance, and trunk control over 12 weeks. Children will be asse…
Phase: NA • Sponsor: Lahore University of Biological and Applied Sciences • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC
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Exercise after nerve surgery may boost trunk control in kids with CP
Disease control CompletedThis study looked at whether physical training after a type of nerve surgery (selective dorsal rhizotomy) can improve trunk control and arm function in children aged 4-7 with severe cerebral palsy who cannot walk. The training included exercises to strengthen the trunk and improv…
Phase: NA • Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Horseback riding or exercise ball: new study tests best balance therapy for kids with cerebral palsy
Disease control CompletedThis study compared two therapies—hippotherapy (therapeutic horseback riding) and Swiss ball exercises—to see which improves trunk control and balance in children with spastic diplegic cerebral palsy. Fifty-two children aged 4 to 11 took part. The goal was to find which approach …
Phase: NA • Sponsor: Riphah International University • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Home trunk training may boost motor skills in children with cerebral palsy
Symptom relief CompletedThis study explores whether a 12-week home-based trunk training program, guided by caregivers, can improve trunk control and gross motor function in children aged 4–12 with spastic diplegic cerebral palsy. Twenty families will test the program, which uses video instructions and w…
Phase: NA • Sponsor: Iqra Khan • Aim: Symptom relief
Last updated Jul 29, 2026 00:00 UTC
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Ultrasound-Enhanced gel and nerve stretching may ease diabetic foot pain
Symptom relief CompletedThis study tests whether applying pregabalin gel through ultrasound (phonophoresis) combined with nerve flossing exercises can reduce pain and improve sensation in people with diabetic peripheral neuropathy. The trial includes 24 adults aged 40–75 who have chronic nerve pain in t…
Phase: NA • Sponsor: Syeda Khatoon e Jannat Welfare Foundation • Aim: Symptom relief
Last updated Jul 24, 2026 00:00 UTC
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Watching and moving: which timing helps kids with CP walk better?
Symptom relief CompletedThis study tested two ways of using action observation therapy to help children with cerebral palsy improve their balance, walking, and daily movement. Twenty-two children aged 6 to 18 watched videos of motor tasks either in real time (synchronous) or with a delay (asynchronous) …
Phase: NA • Sponsor: Istanbul University - Cerrahpasa • Aim: Symptom relief
Last updated Jul 24, 2026 00:00 UTC
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Which exercise helps kids with CP balance better? new study has answers
Symptom relief CompletedThis study tested two exercise methods—core strengthening and movement awareness training—in 32 children with diplegic cerebral palsy (ages 4-8). Both groups did standard physical therapy plus one of the extra exercises three times a week for 12 weeks. The goal was to see which a…
Phase: NA • Sponsor: University of Lahore • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Breathing workouts boost trunk control in kids with cerebral palsy
Symptom relief CompletedThis study looked at whether strengthening breathing muscles can improve trunk control in children with spastic diplegic cerebral palsy. Thirty children aged 8 to 10 took part, doing either standard therapy plus breathing exercises or standard therapy alone for one month. The goa…
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Brain zaps and treadmills: new hope for kids with cerebral palsy?
Symptom relief CompletedThis small study tested a new approach for children with cerebral palsy: combining a gentle brain stimulation technique (tDCS) with treadmill walking. Five children completed ten sessions, and researchers measured changes in walking speed, endurance, and motor skills. The goal wa…
Phase: NA • Sponsor: University of Sharjah • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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New combo therapy shows promise for kids with CP
Symptom relief CompletedThis study tested whether combining TENS (a mild electrical stimulation) with exercises that use sight and body awareness can improve walking in children with spastic diplegic cerebral palsy. Thirty children aged 4 to 6 years old took part. The goal was to see if this approach co…
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Massage tool shows promise for improving gait in kids with CP
Symptom relief CompletedThis study tested whether a technique called instrument-assisted soft tissue mobilization (IASTM) — using a special tool to massage muscles — could improve walking in children with spastic diplegic cerebral palsy. Thirty children aged 5 to 8 took part; half received IASTM plus st…
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Which workout helps kids with cerebral palsy walk better?
Symptom relief CompletedThis study tested two types of exercise—moderate steady training and high-intensity interval training—in 30 children with spastic diplegia (a form of cerebral palsy) aged 3 to 5. The goal was to see which better improves walking, energy use, and daily movement. Children were spli…
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Can watching movements help kids with cerebral palsy move better?
Symptom relief CompletedThis study tested whether watching and imitating movements (action observation therapy) improves balance, walking, and thinking in children with diplegic cerebral palsy compared to standard physical therapy. 46 children aged 5-11 years participated. The goal was to see if this ap…
Phase: NA • Sponsor: Riphah International University • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Mirror neurons at work: simple therapy may improve movement in kids with cerebral palsy
Symptom relief CompletedThis study tested whether Action Observation Therapy—watching a movement and then doing it—can reduce spasticity and improve motor skills, balance, and participation in children with cerebral palsy. 36 children aged 5-13 with spastic diplegia or hemiplegia took part. The therapy …
Sponsor: Suleyman Demirel University • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Bouncing to better balance: new exercise study for kids with cerebral palsy
Symptom relief CompletedThis study tested two exercise programs in 50 children with spastic diplegic cerebral palsy aged 6-12. One group did exercises on unstable surfaces like gym balls and trampolines, while the other did similar exercises on stable surfaces like mats. The goal was to see which approa…
Phase: NA • Sponsor: University of Lahore • Aim: Symptom relief
Last updated Jun 26, 2026 13:07 UTC
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New study explores balance and movement in kids with cerebral palsy
Knowledge-focused CompletedThis study looked at how trunk control, balance, and upper body function are connected in children with cerebral palsy. Researchers measured these abilities in 53 children and compared them to healthy kids. The goal was to better understand these relationships to guide future the…
Sponsor: Eastern Mediterranean University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Anxiety's hidden toll on kids with cerebral palsy
Knowledge-focused CompletedThis study looked at 40 children with cerebral palsy, ages 4 to 8, to see if anxiety is linked to worse balance, muscle stiffness, and movement. Researchers measured anxiety, spasticity, balance, and gross motor function. The goal was to understand these connections better, not t…
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC