Spastic diplegia

This study follows 25 people aged 2 to 65 with cerebral palsy or brain damage from lack of oxygen who have already received a new gene therapy given as a nose spray. The therapy delivers 15 genes meant to repair the brain, reduce inflammation, and improve movement and thinking. R…

This study compares two types of physical therapy for children aged 6 to 10 with diplegic cerebral palsy: scooter board activities and core stability exercises. The goal is to see which better improves trunk control and balance. Forty children will participate, and their progress…

This study tests whether an AI tool can help radiologists read brain CT and MRI scans more accurately and quickly. Researchers will compare how well doctors, AI alone, and doctors using AI together can spot abnormalities, urgent findings, and classify diseases. The goal is to red…

This study tests whether augmented reality (AR) games can improve walking and balance in children with cerebral palsy. Forty children will either do exercises wearing AR goggles or receive standard physical therapy. The goal is to see if the AR approach is more effective and enga…

This trial tests a robotic exoskeleton called the CPWalker to help children with cerebral palsy improve their walking. The device supports the child's weight and assists leg movements during walking practice. The study includes 30 participants aged 11 to 21 with spastic diplegia.…

This study tests whether 3 months of intensive leg exercise (walking, kicking, jumping, and climbing with small ankle weights) can improve walking and daily function in 60 young children with spastic diplegia caused by prematurity. The exercise is done 1 hour a day, 4 days a week…

This study compares two types of therapy for children aged 8 to 12 with spastic diplegic cerebral palsy. One group uses play-based activities like puzzles and arts and crafts, while the other uses standard exercises with resistance bands and weights. The goal is to see which appr…

This study looks at whether walking on a path with lights that show where to step can improve how children with spastic diplegia (a type of cerebral palsy) walk. Thirty children aged 5 to 8 with mild spasticity will walk on the light pathway, and researchers will measure changes …

This study looks at whether doing arm exercises on a vertical surface (like a wall) or a horizontal surface (like a table) makes a bigger difference in hand skills and trunk control for children with bilateral cerebral palsy. Thirty children aged 5 to 8 will take part in a 3-mont…

This study gathers MRI, CT, and ultrasound images from 300 adults—some healthy, some with kidney or brain disease—to build a collection for future not-for-profit research. No new treatments are being tested; the goal is to make medical images available to scientists for advancing…