Spastic diplegia
MONDO:0001167A type of cerebral palsy characterized by spasticity and hypertonia of the lower extremities bilaterally, particularly the legs, hips, and pelvis; this is the most common (70%) form of cerebral palsy.
Also known as: Little disease, Little's disease, diplegic infantile cerebral palsy, cerebral palsy spastic diplegic
58 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Eye workouts may steady the steps of children with cerebral palsy
Disease control OngoingThis trial tests whether structured eye-movement exercises can improve balance and motor skills in children aged 6 to 10 with spastic diplegia, a form of cerebral palsy. Participants perform exercises like tracking moving targets and shifting gaze quickly, alongside standard phys…
Phase: NA • Sponsor: Cairo University • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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Nasal gene therapy offers new hope for brain injury patients
Disease control ENROLLING_BY_INVITATIONThis study follows 25 people aged 2 to 65 with cerebral palsy or brain damage from lack of oxygen who have already received a new gene therapy given as a nose spray. The therapy delivers 15 genes meant to repair the brain, reduce inflammation, and improve movement and thinking. R…
Sponsor: Healing Hope International • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Scooter board fun may beat core exercises for kids with CP
Disease control ENROLLING_BY_INVITATIONThis study compares two types of physical therapy for children aged 6 to 10 with diplegic cerebral palsy: scooter board activities and core stability exercises. The goal is to see which better improves trunk control and balance. Forty children will participate, and their progress…
Phase: NA • Sponsor: Badr University • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Obstacle course training may help children with cerebral palsy walk better
Symptom relief OngoingThis trial tests whether a special training program called Reactive Functional Motor Challenge Training can improve dynamic balance and functional mobility in children with spastic diplegic cerebral palsy. The training uses equipment like balance pads, cones, therapy balls, and a…
Phase: NA • Sponsor: Badr University • Aim: Symptom relief
Last updated Jul 31, 2026 00:00 UTC
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Video goggles could transform physical therapy for children with cerebral palsy
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether augmented reality (AR) games can improve walking and balance in children with cerebral palsy. Forty children will either do exercises wearing AR goggles or receive standard physical therapy. The goal is to see if the AR approach is more effective and enga…
Phase: NA • Sponsor: College of Physical Education and Sport PALESTRA • Aim: Symptom relief
Last updated Jul 02, 2026 00:00 UTC
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Robot walker aims to boost mobility in children with cerebral palsy
Symptom relief OngoingThis trial tests a robotic exoskeleton called the CPWalker to help children with cerebral palsy improve their walking. The device supports the child's weight and assists leg movements during walking practice. The study includes 30 participants aged 11 to 21 with spastic diplegia.…
Phase: NA • Sponsor: Shirley Ryan AbilityLab • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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Leg workouts may boost walking in kids with cerebral palsy
Symptom relief OngoingThis study tests whether 3 months of intensive leg exercise (walking, kicking, jumping, and climbing with small ankle weights) can improve walking and daily function in 60 young children with spastic diplegia caused by prematurity. The exercise is done 1 hour a day, 4 days a week…
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Can playtime beat traditional therapy for kids with cerebral palsy?
Symptom relief OngoingThis study compares two types of therapy for children aged 8 to 12 with spastic diplegic cerebral palsy. One group uses play-based activities like puzzles and arts and crafts, while the other uses standard exercises with resistance bands and weights. The goal is to see which appr…
Phase: NA • Sponsor: University of Lahore • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Glowing footsteps may improve gait in kids with cerebral palsy
Symptom relief OngoingThis study looks at whether walking on a path with lights that show where to step can improve how children with spastic diplegia (a type of cerebral palsy) walk. Thirty children aged 5 to 8 with mild spasticity will walk on the light pathway, and researchers will measure changes …
Phase: NA • Sponsor: Amira saad mohamed • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Could the angle of arm exercises boost hand skills in kids with cerebral palsy?
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether doing arm exercises on a vertical surface (like a wall) or a horizontal surface (like a table) makes a bigger difference in hand skills and trunk control for children with bilateral cerebral palsy. Thirty children aged 5 to 8 will take part in a 3-mont…
Phase: NA • Sponsor: Raghda Gamal Ateya Abd-Elbary • Aim: Symptom relief
Last updated Jun 27, 2026 08:14 UTC