Skin disease caused by bacterial infection

This study tests whether omega-3 supplements or a special anti-demodex eyelid cleanser can help treat and prevent chalazia (styes) in children aged 4 to 17. All 168 participants will use warm compresses, and they will be split into three groups: one adds omega-3 fish oil and stan…

This study tests whether wearing compression stockings alone can prevent repeat episodes of erysipelas (a bacterial skin infection) as well as the usual approach of antibiotics plus stockings. About 200 adults who have had at least two infections in the same leg will be randomly …

This study tests if intense pulsed light (IPL) is a safe and effective way to treat chalazion, a common eyelid lump. About 40 adults with an inflamed chalazion will receive IPL or a control treatment. The main goal is to see if the lump shrinks by at least 80% four weeks after th…

This study looks at whether a blood gas measurement (the difference in carbon dioxide between central venous and arterial blood) can accurately diagnose low cardiac output in patients with septic shock from severe skin infections. About 74 adults will be monitored during hyperbar…

This study tests whether leaving the white, creamy coating (vernix caseosa) on a newborn's skin for at least 24 hours after birth can prevent eczema (atopic dermatitis) during the first year of life. Over 1,300 mother-infant pairs in Chile will be randomly assigned to either keep…

This study will look at 250 people who received the CYFENDUS anthrax vaccine after being exposed to anthrax bacteria during a mass event. Researchers want to see if the vaccine, given along with antibiotics, can prevent inhalational anthrax and anthrax meningitis. The study is ob…

Cellulitis is a painful bacterial skin infection. This study tests whether adding naproxen (an anti-inflammatory drug) to standard antibiotics helps reduce redness and pain faster than antibiotics alone. About 884 adults with cellulitis will take either naproxen or a placebo for …

This pilot study tests whether giving dexamethasone (a steroid) to children hospitalized with orbital cellulitis (a serious eye infection) is worth studying further. Thirty children will receive either dexamethasone or a placebo by IV. The main goal is to see if a larger trial is…

This observational study looks at whether children aged 3 months to 16 years are more likely to complete their full course of antibiotics when prescribed at a primary care clinic versus a hospital emergency department. Researchers surveyed parents by phone after treatment ended t…

This study looks at how the antibiotic delafloxacin spreads through the body in 20 adults with serious skin, soft tissue, bone, or joint infections. Researchers will measure drug levels in blood and in tissues collected during surgery. The goal is to understand if the drug reache…

This study looks at how certain immune cells, called MAIT cells, behave in people with hidradenitis suppurativa (HS), a painful skin condition. Researchers will take skin and blood samples from 45 adults with HS and compare them to samples from people with other skin diseases. Th…