Second-degree atrioventricular block

This study compares two pacemaker methods for people with a slow heart rate: standard right ventricular pacing and a newer 'physiological pacing' that targets the heart's natural conduction system. Researchers will track 2,600 participants over time to see which method better pre…

This study compares two ways of placing a pacemaker lead in people who need frequent pacing. One method (left bundle branch pacing) aims to activate the heart more naturally than the standard method. The goal is to see if it reduces the time the heart spends in fast, irregular rh…

This study tests a new, smaller pacemaker called Micra AV2 in 150 adults with heart block (a condition where the heart's electrical signals are blocked). The pacemaker is designed to better match the heart's natural rhythm, especially during exercise, and lasts over 15 years. Res…

This study is tracking 300 people under age 60 who faint frequently due to a condition called vasovagal syncope. Participants will receive either a nerve ablation procedure (which targets heart nerves) or a permanent pacemaker. The goal is to see which treatment better prevents f…

This study compares two types of portable heart monitors in people who have symptoms of an irregular heartbeat (arrhythmia) but whose standard heart test was normal. About 588 participants will wear either a continuous ECG patch or use a handheld ECG device for one month. The goa…

This study evaluates a new multichannel ECG system designed to detect early signs of cardiovascular disease (CVD) in people who may have no symptoms yet. The system uses advanced algorithms to analyze electrical signals from the heart, looking for subtle abnormalities that could …

This trial is testing whether an artificial intelligence-enhanced electrocardiogram (AI-ECG) can better identify patients who need a cardiac implantable electronic device (like a pacemaker or defibrillator) compared to standard care. Over 11,000 participants will be randomly assi…

This study tests a modified imaging catheter (ViewFlex X ICE) to help doctors see heart structures during procedures for irregular heartbeats. About 500 adults who are already scheduled for a heart procedure using ultrasound will be enrolled. The goal is to see if the new cathete…

This study looks at how a child's quality of life changes after a procedure called transcatheter ablation, which treats abnormal heart rhythms. Researchers will ask 200 children aged 5 to 17 and their parents to fill out questionnaires about physical, emotional, social, and schoo…

This study looks at whether people with heart rhythm problems after a TAVI procedure can safely leave the hospital early if they wear a non-invasive heart monitor at home. About 100 adults who had a successful TAVI for severe aortic stenosis and have certain conduction disorders …

This study will collect ECG recordings from 600 people using the HeartBeam 3-Lead ECG recorder. The goal is to build a database of heart rhythm information for future research and regulatory use. Participants will have their ECG taken as part of routine care, and their de-identif…

This study aims to improve how doctors predict the risk of sudden cardiac death or heart failure in people with inherited heart diseases. Researchers will use artificial intelligence to analyze data from 1,000 participants, including medical history, ECGs, imaging, genetic tests,…

This study looks at whether MRI scans can help predict serious heart events in people who have implanted heart devices like pacemakers or defibrillators. Researchers will scan 1,500 adults before they get their device and track their health for years. The goal is to see if MRI fi…

This study aims to measure how often a heart valve leak (tricuspid regurgitation) develops or worsens after getting a pacemaker or defibrillator with a lead that crosses the valve. About 200 adults who need their first device will have heart ultrasounds before and after the proce…

This study is testing a special heart monitor, the BIOMONITOR IV, in 300 people with heart failure who also have irregular heartbeats. The device tracks heart activity, fluid levels, and breathing patterns to see if it can predict when heart failure gets worse. Researchers hope t…