New pacemaker technique may cut AF risk in heart patients

NCT ID NCT07250529

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two ways of placing a pacemaker lead in people who need frequent pacing. One method (left bundle branch pacing) aims to activate the heart more naturally than the standard method. The goal is to see if it reduces the time the heart spends in fast, irregular rhythms that can lead to atrial fibrillation. About 244 adults with normal heart pumping function will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Left bundle branch pacing (a type of pacemaker lead placement)

What this could lead to

If it works, this could point toward a better pacing method that lowers the risk of developing atrial fibrillation in people who need a pacemaker.

What could go wrong

This is a relatively small, early-stage trial (244 participants) comparing two pacing techniques. The benefit may be modest, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation atrioventricular block heart failure second-degree atrioventricular block third-degree atrioventricular block

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University General Hospital of Patras

    RECRUITING

    Pátrai, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••