New heart procedure could replace pacemakers for fainting patients
NCT ID NCT06166277
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study is tracking 300 people under age 60 who faint frequently due to a condition called vasovagal syncope. Participants will receive either a nerve ablation procedure (which targets heart nerves) or a permanent pacemaker. The goal is to see which treatment better prevents fainting episodes and improves quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- radiofrequency catheter ablation of ganglionated plexi or permanent pacemaker implantation
- What this could lead to
- If successful, this could show that a nerve ablation procedure is a safe and effective alternative to a pacemaker for preventing fainting spells.
- What could go wrong
- This is an observational registry, not a controlled trial, so results may be less definitive. The ablation procedure carries risks like bleeding, infection, or heart rhythm problems.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Rush University Medical Centert
RECRUITINGChicago, Illinois, 60657, United States
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