Postmenopausal osteoporosis

This trial tests whether an experimental biosimilar called 9MW0311 works as well as the established drug Prolia (both containing denosumab) in postmenopausal women with osteoporosis who are at high risk for fractures. Participants receive either 9MW0311 or Prolia as an injection …

This trial investigates whether two common osteoporosis medications, denosumab and alendronate, can reduce liver fat and scarring in postmenopausal women who also have nonalcoholic fatty liver disease (NAFLD). The study will compare changes in liver fat and stiffness over 12 mont…

This study looks at whether adding a statin (atorvastatin or rosuvastatin) to standard osteoporosis treatment can improve bone density in postmenopausal women. Participants are women aged 55 and older with osteoporosis who also have high cholesterol. The trial compares standard t…

This pilot trial tests whether a supervised progressive strength and balance exercise program can reduce falls in postmenopausal women aged 60 to 80 with osteoporosis. Participants are randomly assigned to either the supervised program or a standard home-based exercise routine an…

This study tested whether taking daily probiotics (Lactobacillus plantarum and Lactobacillus paracasei) for 12 months could improve bone density in postmenopausal women with low bone mass. 170 women participated, taking either the probiotic or a placebo. The goal was to see if th…

This phase 3 trial tested a new biosimilar drug called ENZ215 (a form of denosumab) against the established drug Prolia in 504 postmenopausal women with osteoporosis. The goal was to see if ENZ215 works as well as Prolia in improving bone density and reducing bone breakdown marke…

This study looked at whether adding eldecalcitol (a vitamin D-like drug) to denosumab (a bone-strengthening shot) works better than denosumab with regular vitamin D for postmenopausal women with weak bones (osteoporosis). About 100 women took part for 12 months. The main goal was…

This study tested the safety of romosozumab (Evenity) in 100 postmenopausal women in India who have osteoporosis and a high risk of bone fractures. Researchers tracked side effects, serious events, and changes in lab tests and vital signs. They also measured bone density changes …

This phase 3 trial tested whether a biosimilar called Bmab 1000 works as well as the established drug Prolia® for treating osteoporosis in postmenopausal women. 479 women aged 55-79 with osteoporosis received either Bmab 1000 or Prolia® as an injection every 6 months. The study m…

This study looked at whether taking resveratrol (a natural compound found in grapes and red wine) every day could help prevent bone loss in postmenopausal women with low bone mass. 52 women who were 1 to 10 years past menopause took part. Researchers measured bone health through …

This study tested whether atenolol, a widely used beta blocker for heart conditions, can prevent bone loss in postmenopausal women. 420 healthy women aged 50-75 took either atenolol or a placebo daily for a period. The main goal was to see if the drug slowed bone density loss in …

This study tested whether taking a probiotic called Lactobacillus acidophilus can help prevent bone loss and osteoporosis in women after menopause. 90 women aged 45-70 with a BMI between 27 and 35 took either the probiotic or a placebo. Researchers measured calcium levels and bon…

This study looks at whether blood tests called bone turnover markers can quickly show if osteoporosis drugs are working in postmenopausal women. Forty women will receive either bone-strengthening or bone-building medications for six months. The goal is to see if these blood tests…

This study examined 80 postmenopausal women to see if there is a connection between gum (periodontal) disease and osteoporosis. Researchers measured two substances in blood and gum fluid called sclerostin and TNF-α, which may help explain how these conditions affect each other. T…

This study looked at 66 postmenopausal women with osteoporosis who were either taking alendronate (a common bone-strengthening drug) or not. Researchers measured how well the jawbone healed after a tooth extraction using X-rays taken right after, then at 30 and 90 days. The goal …