Postmenopausal atrophic vaginitis
MONDO:0001410Inflammation of the vagina due to thinning of the vaginal wall and decreased lubrication associated with reduced estrogen levels at menopause.
Also known as: atrophic vaginitis, senile vaginitis
48 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Molecular map may guide treatment for mysterious inflammatory illnesses
Disease control CompletedThis study tested whether analyzing a patient's DNA and RNA could help doctors pick the right drug for inflammatory diseases that don't fit standard categories. 32 adults with at least two affected organs (including skin) received one of six targeted therapies based on their mole…
Phase: PHASE2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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New rapid test for infection and inflammation put to the test
Diagnosis CompletedThis study looked at how well a new, quick finger-prick test (LumiraDx CRP) measures CRP levels compared to a standard lab test. CRP is a marker of infection, inflammation, or tissue injury. 79 adults with symptoms of these conditions took part. The goal was to see if the new tes…
Sponsor: LumiraDx UK Limited • Aim: Diagnosis
Last updated Jun 27, 2026 13:07 UTC
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New PET tracer aims to light up hidden infections
Diagnosis CompletedThis early study tested a new radioactive tracer called 18F-FDS in 16 people with suspected bacterial or fungal infections. The tracer is designed to light up infection sites on PET/CT scans, helping doctors see exactly where an infection is. The goal was to check how the tracer …
Sponsor: Johns Hopkins University • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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Can simple exercises ease menopause symptoms? new study says maybe.
Symptom relief CompletedThis study tested whether pelvic floor muscle training combined with patient education can improve genital and urinary symptoms in postmenopausal women. Fifty women participated in an 8-week program that included progressive exercises and information sessions. Researchers measure…
Phase: NA • Sponsor: Hacettepe University • Aim: Symptom relief
Last updated Jun 27, 2026 13:03 UTC
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New combo treatment eases menopause symptoms without hormones
Symptom relief CompletedThis study tested a new treatment for postmenopausal women with vaginal atrophy—a condition causing dryness, burning, and pain. Researchers combined CO₂ laser therapy with a collagen cream to see if it worked better than laser alone. Sixty women aged 35 to 75 took part, and the t…
Phase: NA • Sponsor: Institute for Social Security, Republic of San Marino • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Could a probiotic and laser ease menopause symptoms?
Symptom relief CompletedThis study tested whether a daily probiotic (Lactobacillus crispatus M247) combined with vaginal laser therapy can improve vaginal health and reduce symptoms like dryness, itching, and pain in menopausal women with atrophic vulvovaginitis. 75 women were split into two groups: one…
Phase: NA • Sponsor: Liaquat University of Medical & Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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New light probe offers hope for menopause vaginal pain
Symptom relief CompletedThis study tested a new vaginal probe that uses special lights to treat vaginal atrophy in 25 postmenopausal women who had not been helped by other treatments. The probe aims to reduce pain and dryness by stimulating natural tissue repair. The main goal was to check safety and se…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Could a shot of your own blood ease menopause symptoms?
Symptom relief CompletedThis study tests whether injecting platelet-rich plasma (PRP) from a woman's own blood into the vulvovaginal area can relieve symptoms of genital atrophy like dryness, burning, and pain during sex. It includes 30 women who cannot use standard hormone treatments. Half receive PRP …
Phase: PHASE1, PHASE2 • Sponsor: AndreiaAntunes • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Study explores how family and friends impact caregiver health
Knowledge-focused CompletedThis completed study looked at how the social networks of caregivers affect their stress and health when caring for someone with an inherited disease. Researchers surveyed over 680 participants, including family members and formal caregivers, to understand caregiving burden and s…
Sponsor: National Human Genome Research Institute (NHGRI) • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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New tool measures the Real-Life impact of vaginal aging in portuguese women
Knowledge-focused CompletedThis study tested a Portuguese version of the DIVA questionnaire to see if it reliably measures how vaginal aging symptoms (like dryness, itching, or pain) affect daily activities, sex life, emotions, and body image. 300 women with at least one symptom of vulvovaginal atrophy too…
Sponsor: Instituto Politécnico de Leiria • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Can vaginal estrogen be safe for breast cancer survivors? new study investigates
Knowledge-focused CompletedThis study looked at whether a low-dose vaginal estrogen tablet (Vagifem) is safe for women who have had breast cancer and are taking aromatase inhibitors. 31 postmenopausal women with a history of breast cancer used the tablet for vaginal dryness. Researchers measured their bloo…
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Could a menopause drug change how the brain responds to sex?
Knowledge-focused CompletedThis study looked at whether ospemifene, a non-hormonal drug for vaginal dryness, also affects brain activity in postmenopausal women with sexual interest-arousal disorder. Twenty-five women took the drug or a placebo and underwent brain scans while watching sexual videos or smel…
Phase: PHASE4 • Sponsor: Hospital Clinic of Barcelona • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:59 UTC