Postmenopausal atrophic vaginitis
MONDO:0001410Inflammation of the vagina due to thinning of the vaginal wall and decreased lubrication associated with reduced estrogen levels at menopause.
Also known as: atrophic vaginitis, senile vaginitis
38 clinical trials for this condition and its sub-types.
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Could gentle radio waves ease menopause symptoms?
Symptom relief CompletedThis study tests whether a non-ablative radiofrequency treatment can improve vaginal tissue health and reduce symptoms of Genitourinary Syndrome of Menopause (GSM), such as dryness and discomfort, in postmenopausal women. Participants will be randomly assigned to receive either t…
Phase: NA • Sponsor: University of Castilla-La Mancha • Aim: Symptom relief
Last updated Aug 18, 2026 05:00 UTC
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New hope for breast cancer survivors: trial tests vaginal treatments for hormone therapy side effects
Symptom relief CompletedThis study tests four different vaginal treatments (estrogen, DHEA, estrogen with probiotics, and a moisturizer) in 160 breast cancer patients who have vaginal atrophy due to hormone therapy. The goal is to see which treatment best relieves symptoms like dryness and pain, and imp…
Phase: PHASE4 • Sponsor: University Hospital, Ghent • Aim: Symptom relief
Last updated Aug 15, 2026 00:00 UTC
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New cream aims to boost laser therapy results for vaginal atrophy
Symptom relief CompletedThis study is testing whether a daily cream (7-0940®) can safely improve symptoms of vaginal atrophy in 10 women who have already completed laser therapy. Researchers will check vaginal health, quality of life, and any side effects over 45 days. The goal is to see if the cream he…
Phase: PHASE4 • Sponsor: Stratpharma AG • Aim: Symptom relief
Last updated Jul 22, 2026 00:00 UTC
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Can simple exercises ease menopause symptoms? new study says maybe.
Symptom relief CompletedThis study tested whether pelvic floor muscle training combined with patient education can improve genital and urinary symptoms in postmenopausal women. Fifty women participated in an 8-week program that included progressive exercises and information sessions. Researchers measure…
Phase: NA • Sponsor: Hacettepe University • Aim: Symptom relief
Last updated Jun 27, 2026 13:03 UTC
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New combo treatment eases menopause symptoms without hormones
Symptom relief CompletedThis study tested a new treatment for postmenopausal women with vaginal atrophy—a condition causing dryness, burning, and pain. Researchers combined CO₂ laser therapy with a collagen cream to see if it worked better than laser alone. Sixty women aged 35 to 75 took part, and the t…
Phase: NA • Sponsor: Institute for Social Security, Republic of San Marino • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Could a probiotic and laser ease menopause symptoms?
Symptom relief CompletedThis study tested whether a daily probiotic (Lactobacillus crispatus M247) combined with vaginal laser therapy can improve vaginal health and reduce symptoms like dryness, itching, and pain in menopausal women with atrophic vulvovaginitis. 75 women were split into two groups: one…
Phase: NA • Sponsor: Liaquat University of Medical & Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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New light probe offers hope for menopause vaginal pain
Symptom relief CompletedThis study tested a new vaginal probe that uses special lights to treat vaginal atrophy in 25 postmenopausal women who had not been helped by other treatments. The probe aims to reduce pain and dryness by stimulating natural tissue repair. The main goal was to check safety and se…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Could a shot of your own blood ease menopause symptoms?
Symptom relief CompletedThis study tests whether injecting platelet-rich plasma (PRP) from a woman's own blood into the vulvovaginal area can relieve symptoms of genital atrophy like dryness, burning, and pain during sex. It includes 30 women who cannot use standard hormone treatments. Half receive PRP …
Phase: PHASE1, PHASE2 • Sponsor: AndreiaAntunes • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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New tool measures the Real-Life impact of vaginal aging in portuguese women
Knowledge-focused CompletedThis study tested a Portuguese version of the DIVA questionnaire to see if it reliably measures how vaginal aging symptoms (like dryness, itching, or pain) affect daily activities, sex life, emotions, and body image. 300 women with at least one symptom of vulvovaginal atrophy too…
Sponsor: Instituto Politécnico de Leiria • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Can vaginal estrogen be safe for breast cancer survivors? new study investigates
Knowledge-focused CompletedThis study looked at whether a low-dose vaginal estrogen tablet (Vagifem) is safe for women who have had breast cancer and are taking aromatase inhibitors. 31 postmenopausal women with a history of breast cancer used the tablet for vaginal dryness. Researchers measured their bloo…
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Could a menopause drug change how the brain responds to sex?
Knowledge-focused CompletedThis study looked at whether ospemifene, a non-hormonal drug for vaginal dryness, also affects brain activity in postmenopausal women with sexual interest-arousal disorder. Twenty-five women took the drug or a placebo and underwent brain scans while watching sexual videos or smel…
Phase: PHASE4 • Sponsor: Hospital Clinic of Barcelona • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:59 UTC