Postmenopausal atrophic vaginitis
MONDO:0001410Inflammation of the vagina due to thinning of the vaginal wall and decreased lubrication associated with reduced estrogen levels at menopause.
Also known as: atrophic vaginitis, senile vaginitis
38 clinical trials for this condition and its sub-types.
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Can vaginal estradiol or moisturizer ease menopause symptoms in women with HIV?
Disease control Not yet recruitingThis study compares vaginal estradiol tablets (Vagifem) to a vaginal moisturizer (Replens) for treating menopause-related vaginal and urinary symptoms in women living with HIV. Researchers will also check how these treatments affect the vaginal microbiome. The study includes 62 p…
Phase: PHASE4 • Sponsor: Albert Einstein College of Medicine • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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Blue light could soothe vaginal disorders without hormones
Disease control Not yet recruitingThis study tests whether blue LED light therapy can improve symptoms of common vaginal conditions like menopause-related dryness, bacterial vaginosis, and yeast infections. About 150 women aged 18 to 75 will receive the treatment either at home or in a clinic. Researchers will ch…
Phase: NA • Sponsor: Patricia Lordelo • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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Could a single injection ease vaginal dryness? new trial tests hyaluronic acid gel
Symptom relief Not yet recruitingThis trial tests F-GYN, a single-use injectable gel made of non-crosslinked hyaluronic acid, for women with moderate to severe vaginal dryness and atrophy. Participants either receive the injection right away or continue standard non-hormonal care for 4 weeks before getting the i…
Phase: NA • Sponsor: Biovico Sp. z o.o. • Aim: Symptom relief
Last updated Jul 16, 2026 00:00 UTC
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Could radio waves ease menopause symptoms? new trial investigates
Symptom relief Not yet recruitingThis study tests whether a non-surgical radiofrequency device can improve vaginal health and sexual function in postmenopausal women. Forty women aged 40-65 will receive either active treatment or a sham procedure over six weekly sessions. The goal is to see if this approach safe…
Phase: NA • Sponsor: University of Castilla-La Mancha • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Ancient herb mix may soothe menopause discomfort
Symptom relief Not yet recruitingThis early-phase trial will test whether a Chinese herbal formula called TJAOA103 can relieve genitourinary symptoms of menopause, such as vaginal dryness, itching, and pain during sex. About 113 women aged 45-70 will take the herbal drink twice daily for 4 to 12 weeks. Researche…
Phase: EARLY_PHASE1 • Sponsor: Tongji Hospital • Aim: Symptom relief
Last updated Jun 26, 2026 18:18 UTC
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Could a collagen pill ease menopause discomfort?
Symptom relief Not yet recruitingThis study tests whether a daily oral supplement containing bioactive collagen peptides can improve quality of life for menopausal women with vaginal dryness, pain, and mild urinary incontinence. 43 women will take the supplement for 16 weeks and report changes in symptoms and se…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Symptom relief
Last updated Jun 26, 2026 13:21 UTC
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Can a gel ease menopause symptoms that disrupt daily life?
Knowledge-focused Not yet recruitingThis study examines the most common symptoms of genitourinary syndrome of menopause (GSM) in postmenopausal women and how these symptoms impact quality of life. Researchers will also look at whether using a non-hormonal topical gel called XCM INTIM for at least 8 weeks is linked …
Sponsor: Mucosa Innovations, S.L. • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC