Postmenopausal atrophic vaginitis

This study tests whether a pharmacist-led program can help people reduce their risk of heart disease. Over 1,000 adults with conditions like diabetes, high blood pressure, or obesity are taking part. Pharmacists use a step-by-step guide to assess risk and support lifestyle change…

This phase 2 trial tests whether injecting platelet-rich plasma (PRP) into the vulva and vagina can improve symptoms of genitourinary syndrome of menopause (GSM) in breast cancer survivors. GSM causes dryness, burning, and pain, often worsened by cancer treatments. The study enro…

This study aimed to see if adding a hyaluronic acid-based vaginal moisturizer to standard vaginal estrogen therapy provides extra relief for menopause-related vaginal symptoms. It planned to enroll postmenopausal women aged 45 and older who had not used these treatments recently.…

This study tests four different vaginal treatments (estrogen, DHEA, estrogen with probiotics, and a moisturizer) in 160 breast cancer patients who have vaginal atrophy due to hormone therapy. The goal is to see which treatment best relieves symptoms like dryness and pain, and imp…

This study tests a non-hormonal laser treatment for genitourinary syndrome of menopause (GSM) in women who have completed cancer treatment. GSM causes symptoms like vaginal dryness and pain, which can affect quality of life. The study will compare the laser therapy to a control g…

This study tests a gel called Hyalo Gyn® to see if it helps with vaginal dryness in women who have had breast cancer and are past menopause. About 156 women will use the gel or a placebo every three days for 12 weeks. The goal is to see if the gel reduces dryness and other sympto…

This study tests a device called INNEA AQUA, used in the vagina, to see if it safely reduces symptoms of vulvo-vaginal atrophy (VVA) in adult women. VVA can cause itching, soreness, and pain during sex. The trial compares the device to standard care in 62 women aged 18-75. Resear…

This study looks at two treatments for vaginal dryness in women with estrogen receptor-positive breast cancer who are taking aromatase inhibitors. One group uses a vaginal estrogen ring that releases a low dose of estrogen over 90 days, while the other uses a non-hormonal vaginal…

This study tests whether injecting platelet-rich plasma (PRP) — made from a woman's own blood — into the vaginal wall can improve sexual function and reduce dryness caused by menopause. Thirty postmenopausal women with genitourinary syndrome of menopause will receive either PRP o…

This study follows up to 500 people with acute or chronic inflammatory disorders, such as infections or immune problems, over time. Researchers will monitor participants with standard tests and may screen them for other studies. The goal is to better understand these conditions a…

This study collects blood, urine, and tissue samples from 330 adults with advanced lung or head and neck cancer to improve precision medicine. Researchers will analyze genetic changes in these samples and grow some tumors in mice to compare DNA. The goal is to refine liquid biops…

This study watches a single gynecology resident as they learn to perform a hysterectomy through the vagina using a special camera, leaving no belly scars. The goal is to see how quickly the resident improves, measuring surgery time and any complications. Nineteen women with benig…

This study is creating a biobank—a collection of blood samples and health data—to help researchers better understand gynecological disorders, infertility in men and women, and pregnancy-related conditions. Up to 3,000 participants will provide samples at San Raffaele Hospital in …