Pituitary dwarfism

This study tests an oral medication called LUM-201 in children with growth hormone deficiency who have not yet received treatment. The goal is to see if taking a pill daily can improve growth as effectively as standard daily injections. The trial also looks for a way to identify …

This study tested an oral drug called LUM-201 in 15 children with growth hormone deficiency who had already received daily injections for a year. The goal was to see if LUM-201 could maintain or improve growth over 12 months. The drug was given once daily by mouth, and researcher…

This study tested a once-weekly injection called lonapegsomatropin in 220 adults with growth hormone deficiency who had already completed a previous trial. The goal was to see if the drug remains safe and effective over a full year. Participants received the injection for 52 week…

This study looked at whether growth hormone therapy can improve muscle strength, power, and body composition in short prepubertal boys, both those with growth hormone deficiency and those with idiopathic short stature. Thirty short boys received growth hormone injections for 12 m…

This completed observational study at Uşak University examined 150 adults hospitalized in the endocrinology department. Researchers measured breathing, muscle strength, pain, fatigue, sleep quality, physical activity, balance, and nerve function. The goal was to better understand…

This study looked at 500 children who had surgery for a rare brain tumor called craniopharyngioma. Researchers used MRI scans to grade how much the tumor damaged a key brain area (the hypothalamus). They found that more damage was linked to higher rates of growth hormone deficien…

This completed study looked at whether a blood test for a substance called ADMA can measure blood vessel health in children with growth hormone deficiency or those born small for their age. Researchers compared ADMA levels to ultrasound measurements of artery function in 23 child…

This completed study involved 40 families of children with growth hormone deficiency. Researchers used data from connected injector devices and family surveys to develop a personalized growth hormone treatment profile (PGTP) report. The goal is to help doctors create more tailore…

This study measured the biological (epigenetic) age of 10 children with growth hormone deficiency before and after 6 months of hormone therapy. Researchers wanted to see if treatment changes how old their cells appear. The goal is to better understand growth hormone's effects on …