Could a pill replace daily shots for growth hormone deficiency?

NCT ID NCT05250063

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an oral drug called LUM-201 in 15 children with growth hormone deficiency who had already received daily injections for a year. The goal was to see if LUM-201 could maintain or improve growth over 12 months. The drug was given once daily by mouth, and researchers measured height changes and monitored for side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

LUM-201 (oral drug)

What this could lead to

If successful, this could offer a more convenient oral treatment option for children with growth hormone deficiency, reducing the need for daily injections.

What could go wrong

This is a small, early-phase study with only 15 participants, so results may not apply to all children. The drug may not work as well as current treatments or could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

isolated congenital growth hormone deficiency pituitary dwarfism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Children's National Hospital

    Washington D.C., District of Columbia, 20010, United States

  • Indiana University School of Medicine

    Indianapolis, Indiana, 46202, United States

  • Klinika Endokrynologii i Chorob Metabolicznych, Instytut Centrum Zdrowia Matki Polki

    Lodz, Poland

  • Klinika Endokrynologii i Diabetologii, Instytut "Pomnik Centrum Zdrowia Dziecka

    Warsaw, Poland

  • M Health, Fairview Pediatric Specialty Clinics- Discovery Clinic

    Minneapolis, Minnesota, 55454, United States

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

  • Rady Children's Hospital

    San Diego, California, 92123, United States

  • Sonomed - Centrum Medyczne

    Szczecin, Poland

  • The Children's Mercy Hospital

    Kansas City, Missouri, 64111, United States

  • University of Virginia Health System

    Charlottesville, Virginia, 22908, United States