Nutritional deficiency disease

This trial tests whether adding a twice-daily nutritional drink to standard care helps adults aged 55 and older regain weight and muscle strength after being hospitalized for an acute illness. Participants are at risk of malnutrition and have low grip strength. Half receive the d…

This study tests whether giving caregivers a weekly bulk container (7-day supply) versus daily single-use sachets (1-day supply) of a nutrient supplement improves how much children actually consume. About 500 caregivers of children aged 6-24 months in northern Ghana will try both…

This study tests whether a 12-day nutrition education program, called Positive Deviance/Hearth (PDH), can help children aged 6-59 months recover from moderate acute malnutrition. Caregivers learn to prepare nutrient-dense meals using local ingredients, with follow-up support. The…

This study tests whether a special omega-3-enriched nutritional drink can improve nutrition in people with advanced lung or colorectal cancer who are at risk of malnutrition. About 118 participants will either get the drink plus dietary advice, or just dietary advice alone. The g…

This study tests whether high-calorie diets and special nutritional formulas can help underweight children aged 1 to 5 with congenital heart disease gain weight. Seventy-five children will be split into three groups: standard diet, high-calorie diet, or high-calorie diet plus a s…

This study tests a new, energy-rich therapeutic food for children aged 6 to 59 months with severe acute malnutrition. Researchers want to see if it helps kids recover physically and improves their brain development compared to the standard food. About 125 children in Pakistan wil…

This study tests whether a structured exercise and nutrition plan can help older patients (70+) avoid losing the ability to care for themselves during a hospital stay. About 360 patients from a geriatric ward will take part. The goal is to see if personalized resistance and mobil…

This study looks at whether providing nutritional support to hospitalized patients who are at risk of malnutrition can lead to better health outcomes and be cost-effective. About 400 adults staying overnight in the hospital will take part. Researchers will track infections and to…

This study tests whether a daily supplement made from mealworm flour can improve the nutritional health of 40 children aged 2-10 with chronic malnutrition in the Democratic Republic of the Congo. One group will receive the mealworm supplement, while the other gets a traditional c…

This study looks at whether giving extra nutrition during dialysis sessions helps people on long-term hemodialysis build muscle and manage blood pressure. Researchers will compare the effects of this special nutrition with usual care in 16 adults who have been on dialysis for at …

This study tests whether combining a home exercise program with a daily anti-inflammatory nutritional supplement (Alisenoc™) can improve physical performance in frail, malnourished adults aged 75 and older. Participants will be randomly assigned to receive either the anti-inflamm…

Researchers in Lahore, Pakistan are testing whether providing a daily balanced school meal to children aged 6 to 11 can improve their nutritional status and academic performance. Over 12 weeks, some children will receive a meal covering about one-third of their daily energy needs…

This study in Ethiopia tests whether a new 7-day package of a nutritional supplement (SQ-LNS) works as well as the usual daily packets for preventing malnutrition in children aged 6-24 months. Researchers will compare how well families stick to using each package type over 8 week…

This trial tests whether listening to a 15-minute relaxation audio during breastfeeding, twice daily for 12 weeks, can improve weight gain in low-birth-weight newborns and reduce maternal stress and anxiety. Mothers of stable infants born under 2500 grams will be randomly assigne…

This trial tests whether adding a structured nutrition and exercise program to the standard appetite-stimulating drug olanzapine can improve quality of life in people with advanced solid tumors who have poor appetite. Participants are randomly assigned to receive olanzapine alone…

This Phase 2 trial tests whether a drug called nanocrystalline megestrol acetate can help people with advanced liver cancer who are losing weight and appetite. About 88 patients will receive either the drug or a placebo for 12 weeks while also getting standard cancer therapy. The…

This study tests whether silkworm pupa tablets can improve nutrition and reduce muscle loss (sarcopenia) in people who have completed cancer treatment. 480 participants will receive either the tablets or a placebo for 3 months. The main goal is to see if muscle strength and mass …

This study tests a 12-week program that provides medically tailored meals and coaching from a dietitian to children undergoing cancer treatment and their caregivers. The goal is to see if the program is practical and helpful for improving nutrition and reducing caregiver stress. …

Researchers at Assiut University are studying how to identify malnutrition in critically ill children aged 1 month to 5 years admitted to a pediatric intensive care unit. The team uses a four-part ABCD approach that combines body measurements, blood markers, physical signs, and d…

This pilot study will check if it's possible to collect useful nutrition and health information from 30 adults with diabetic foot ulcers. Researchers want to see if they can recruit enough people and gather complete data. The goal is to learn about patients' diet, body compositio…

This study tests whether giving breastfeeding mothers a daily iodine-containing multivitamin for 6 months helps their babies' brains and thyroid health. Researchers will compare babies' brain activity and development between moms who get the supplement and those who receive stand…

This study looks at elderly patients (60 and older) with COPD who need a breathing machine in the ICU. Researchers will check their nutritional status and measure the thickness of their diaphragm muscle using ultrasound. The goal is to see if these factors can predict how well pa…

This study looks at whether nutritional risk and muscle thickness can help predict recovery in adults aged 65 and older after hip fracture surgery. Researchers will measure nutritional status using a standard score and check muscle thickness in the thigh with a quick, painless ul…

This study tests whether 3D infrared body scanning can better assess malnutrition in adolescents and young adults hospitalized with anorexia nervosa. Researchers will measure body composition and track how organ and tissue stores relate to medical stability, nutritional needs, an…

This study looks at the nutritional health of people aged 65 and older who are hospitalized with mental disorders. Researchers will assess conditions like malnutrition, frailty, and obesity, and use the findings to design a practical care pathway for nutritional support. The goal…

This study investigates refeeding syndrome, a dangerous metabolic complication that can occur when severely malnourished patients start receiving nutrition again. Researchers will give a mixed-meal tolerance test to 15 adults who need a feeding tube after a month of very low food…

This study looks at why some older adults lose their appetite while others keep a healthy one. Researchers will measure how taste, digestion, and hormones differ between the two groups. Twenty women aged 65-74 will take part. No treatment is given; the goal is simply to learn mor…

This study follows 120 malnourished adults undergoing major abdominal or pelvic cancer surgery to see how their gut function, nutrition, and risk of confusion (delirium) change in the first week after surgery. Researchers will also check if giving a natural chemical called seroto…

This study in Assiut, Egypt, will check 116 children aged 2-15 for intestinal parasites to see if these infections are more common in malnourished kids compared to healthy ones. The goal is to understand how parasites like Giardia and hookworms might cause or worsen malnutrition …

This study tests a 3D-printed camera attachment that helps dental students take consistent, high-quality photos of teeth. The goal is to see if it improves the accuracy of dental records and nutrition knowledge. Four hundred dental students in Egypt will use either the new tool o…

This study tests whether giving less therapeutic food and requiring fewer clinic visits can still effectively treat severe acute malnutrition in children aged 6-59 months in Kenya. About 2,274 children will take part across 45 health facilities. The goal is to find a treatment ap…

This study aims to create a nutrition algorithm called NACHO that suggests foods and recipes tailored to cancer patients' needs. Researchers will work with dietitians, clinicians, and patient advisors to develop the tool, then test it with 130 patients who are undergoing or have …

This study will check the health, nutrition, and daily living abilities of 330 older adults (age 60+) living in a rural village in Assiut, Egypt. Researchers will interview participants and take simple physical measurements like weight and blood pressure. No treatments are given—…

This study looks at whether older adults (70+) with low muscle mass are more likely to have serious bleeding while taking common blood thinners (apixaban or rivaroxaban). Researchers will compare muscle mass in 110 patients who had a bleeding event with those who did not. The goa…