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Could a simple ultrasound predict ventilator success in elderly COPD patients?

NCT ID NCT07788170

Knowledge-focused Sponsor: Assiut University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
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Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 26, 2026 · Last updated Aug 27, 2026 · Updated 1 time

Summary

This study looks at elderly patients (60 and older) with COPD who need a breathing machine in the ICU. Researchers will check their nutritional status and measure the thickness of their diaphragm muscle using ultrasound. The goal is to see if these factors can predict how well patients do, such as how long they need the ventilator and their chances of recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors identify which elderly COPD patients on ventilators are at higher risk of complications, potentially guiding earlier nutritional support and respiratory care.
What could go wrong
This is an observational study, so it cannot prove cause and effect. Results may not apply to all patients, and the measurements may vary between operators.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Nov 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Elderly patients aged 60 years or older with acute exacerbation of chronic obstructive pulmonary disease (COPD) admitted to the Chest Department and ICU/respiratory ICU at Assiut University Hospital who require invasive mechanical ventilation for at least 48 hours.

Ages

60 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients aged ≥ 60 years * Confirmed diagnosis of Chronic Obstructive Pulmonary Disease (COPD) according to GOLD (Global Initiative for Chronic Obstructive Lung Disease) criteria * Admission to the intensive care unit (ICU) or respiratory ICU for acute exacerbation of COPD * Requirement for invasive mechanical ventilation for ≥ 48 hours * Provision of informed consent by the patient or a first-degree relative/legal guardian Exclusion Criteria: * Pre-existing neuromuscular disease affecting diaphragmatic or peripheral muscle function (e.g., myasthenia gravis, muscular dystrophy, poliomyelitis, motor neuron disease) * Known diaphragmatic paralysis or phrenic nerve injury predating admission * Severe limb edema, amputation, or lower-limb deformity precluding valid anthropometric measurement * Terminal illness or malignancy with an expected survival of \< 48 hours * Duration of mechanical ventilation \< 48 hours, or death/extubation occurring before baseline assessment completion * Subcutaneous emphysema or thoracic/abdominal wall pathology precluding adequate diaphragmatic ultrasound acoustic windows

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease Malnutrition nutritional deficiency disease respiratory failure Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute exacerbation of chronic obstructive pulmonary disease Chronic obstructive pulmonary disease (COPD) Malnutrition Respiratory failure Ventilator-induced diaphragmatic dysfunction

How to take part

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  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

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