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Can a simple ultrasound combo predict breathing failure before it happens?

NCT ID NCT07807566

Diagnosis Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 08, 2026 · Last updated Sep 09, 2026 · Updated 1 time

Summary

Blunt chest trauma can lead to serious breathing problems, but current imaging tools have limits. This study tests whether adding a diaphragm ultrasound to the standard lung ultrasound helps doctors predict which patients will develop hypoxemic respiratory failure. Adults with isolated blunt chest trauma will receive both ultrasound exams and blood gas tests at four time points within the first 24 hours. The goal is to see if this bedside, radiation-free approach identifies high-risk patients earlier than lung ultrasound alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Combined lung and diaphragmatic ultrasound
What this could lead to
If it works, this could give emergency doctors a bedside, radiation-free way to spot high-risk patients earlier and guide timely breathing support.
What could go wrong
This is an observational study, not a treatment trial. It may not prove that the combined ultrasound improves patient outcomes, and results depend on the skill of the person performing the scans.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 130 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Nov 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients presenting to the emergency room of the Trauma Unit at Assiut University Hospitals within 24 hours of sustaining isolated blunt chest trauma.

Ages

18 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older * Presentation to the trauma unit within 24 hours of injury * Diagnosed with isolated blunt chest trauma * Willingness to participate with written informed consent provided by the patient or legally authorized representative Exclusion Criteria: * Penetrating chest trauma * Immediate endotracheal intubation before baseline ultrasound assessment * Massive hemothorax or tension pneumothorax requiring immediate emergency intervention prior to ultrasound evaluation * Inadequate ultrasound acoustic window due to extensive subcutaneous emphysema or severe obesity * Known preexisting chronic pulmonary disease (e.g., chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, bronchial asthma) * Known preexisting cardiac disease (e.g., ischemic heart disease, rheumatic heart disease) * Known neuromuscular disorders affecting respiratory muscles * Previous thoracic surgery affecting diaphragmatic excursion or documented diaphragmatic paralysis * Pregnancy * Refusal to provide informed consent or withdrawal from the study

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Conditions

The condition(s) this trial relates to.

respiratory failure Thoracic Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Blunt chest trauma Hypoxemic respiratory failure Respiratory failure Thoracic injuries

How to take part

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  1. The official record

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