Language disorder

This study tests whether leucovorin calcium, a vitamin-like supplement, can improve language and other symptoms in young children with autism spectrum disorder. Researchers will enroll 80 children aged 2.5 to 5 years with language delays. The trial lasts about 26 weeks and compar…

This study tests a drug called neflamapimod in 20 people with a language disorder called nonfluent variant primary progressive aphasia (nfvPPA). The goal is to see if the drug is safe and if it can improve language symptoms. Participants will receive either the drug or a placebo …

This study explores whether joining a weekly reading group can improve reading comprehension and communication confidence in adults with aphasia, a language disorder often caused by stroke. Participants read a book at home and then discuss it in a 90-minute group session each wee…

This study explores whether adding a non-invasive brain stimulation technique called transcranial direct current stimulation (tDCS) to standard speech therapy can improve word-finding in people with aphasia after a stroke. The trial involves 50 adults who are at least six months …

This study tests whether 80 sessions of a gentle brain stimulation technique called tDCS, given over 12 months, can improve attention, social skills, and language in 180 children aged 6 to 11 who have autism along with rare diseases, genetic problems, or PANDAS. The treatment is …

This study looks at whether changing the sound of your own voice (like adding echo or whisper) can help adults who stutter speak more smoothly. About 100 people will use a special app for one month. The goal is to see if this simple technique improves fluency over time.

This study tests whether a non-invasive device that gently stimulates the vagus nerve through the ear can improve speech recovery in people with aphasia after stroke or brain injury. Twelve adults with apraxia of speech will receive either active or sham stimulation during 16 wee…

This study tests whether folinic acid (leucovorin), a drug already used to reduce side effects from chemotherapy, can improve language skills in children with autism spectrum disorder. Researchers will give the drug or a placebo to 56 children aged 5 to 17 for 12 to 24 weeks and …

This study tests whether watching immersive 360° videos of everyday actions can improve word-finding in people with anomic aphasia after a stroke. Forty participants will either watch first-person 360° videos or standard third-person videos over 12 sessions. The goal is to see if…

This study tests whether a mild electrical current applied to the brain (tDCS) during speech therapy can improve language recovery in people with aphasia after a stroke. Two hundred adults with language problems from left-brain damage will receive either real or fake stimulation …

This study compares virtual reality-supported speech therapy to traditional speech therapy in 100 children aged 3 to 6 with developmental language disorder. Each child receives the same amount of therapy, but one group uses a VR system with touchscreen exercises while the other u…

This study tests a 22-week small-group program called Let's Know!2 for first graders with low language skills. The program uses fun lessons to build vocabulary and comprehension. Researchers will compare children who get the program to those who don't, tracking their progress thr…

This study tests two types of speech therapy for people with primary progressive aphasia, a brain disorder that slowly destroys language skills. Sixty participants will work on word retrieval or script practice with a clinician and at home. Researchers will measure changes in com…

This study tests a speech-language telerehabilitation program for people with primary progressive aphasia (PPA), a dementia that slowly destroys language abilities. The program includes online therapy sessions and care partner training. Researchers will enroll 21 participants to …

This study looks at whether genes and thinking skills like memory can predict how well someone with aphasia (trouble speaking after a stroke) responds to word-retrieval therapy. Researchers will work with 120 people who had a stroke at least six months ago. The goal is to move to…

This study follows children aged 6 to 21 who have a CNKSR2 gene mutation, which can cause epilepsy, language difficulties, and intellectual disability. Researchers will use brain scans, EEGs, and developmental tests to track how the condition changes over time. The goal is to cre…

This study tests a computer-based word retrieval practice for people with aphasia, a language disorder often caused by stroke. Twenty adults who have trouble finding words will practice naming pictures with feedback. The goal is to see if this practice can improve word retrieval …

This study trains police officers and first responders to better communicate with people who have aphasia, a condition that affects speech and understanding. 75 participants from the Madison Police Department will take part for up to 6 months. The goal is to see if training impro…

This study compares 6 months of group music activities versus circus activities in 200 infants (8-12 months old) with or without a family history of dyslexia. Researchers will measure language skills, brain responses to sounds, and social-emotional factors. The goal is to see if …

This study looks at how the brain's temporal lobe helps process sound. Researchers will measure brain activity using EEG in 10 people who have had surgery to remove a lesion in a key hearing area. The goal is to better understand how the brain generates electrical responses to sp…

This study aims to learn more about diseases that affect the brain, such as Parkinson's disease and different types of dementia. Researchers will follow 500 adults with symptoms of these conditions over time, using brain scans and genetic tests to see how the diseases progress. T…