Inherited auditory system disease

This early-stage trial tests a new cell therapy called Rincell-1 for adults with certain types of hearing loss who are getting a cochlear implant. The study will compare the safety and early effectiveness of receiving the cell therapy plus the implant versus the implant alone. Ab…

This study tests a surgical procedure called endoscopic stapedotomy for people with otosclerosis, a condition that causes progressive hearing loss. Surgeons will use a tiny camera to place a small artificial device in the middle ear to improve sound transmission. The study will f…

This study tests whether Ai Chi, a slow, controlled water exercise program, can help people with long-term dizziness from inner ear problems. 38 adults will either do standard home exercises or add Ai Chi sessions in a pool over 4 weeks. Researchers will measure changes in balanc…

This study tests whether special eye and balance exercises can reduce dizziness, motion sickness, and improve quality of life in people with inner-ear balance problems. Thirty-two adults with motion sickness or vertigo will do either standard habituation exercises or a new optoki…

This study tests whether rimegepant, a drug used for migraines, can quickly reduce dizziness from conditions like vestibular migraine. About 370 adults with moderate to severe dizziness will receive either rimegepant plus betahistine or betahistine alone. The main goal is to see …

This study compares two ways to insert a cochlear implant: using a robotic device or the standard manual method. Researchers want to see which approach leads to better hearing one year after surgery. The study will enroll 32 adults with hearing loss, randomly assigning them to on…

This study tests a new care pathway for adults getting a cochlear implant. Instead of the usual nine clinic visits in the first year, the new plan uses early activation of the implant and remote monitoring visits. The goal is to see if this approach is at least as good for hearin…

This study will measure balance, coordination, and reaction time in 41 adults aged 18-40 who experience motion sickness. Participants will complete a series of physical tests and a controlled motion sickness provocation session. The goal is to see how these sensorimotor skills re…

This study looks at 10 adults over 50 with hearing loss and one weak balance ear. It compares implanting the device in the weak-balance ear versus the good-balance ear. The goal is to see if choosing the weaker side helps reduce dizziness after surgery.

This study looks at how taking caffeine in different ways—daily low doses, gradually increasing doses, or only on workout days—affects muscle growth and strength in 180 young men who don't normally drink caffeine or exercise with weights. Participants will follow two 4-week super…