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Hemiplegia
MONDO:0001170Severe or complete loss of motor function on one side of the body. This condition is usually caused by brain diseases that are localized to the cerebral hemisphere opposite to the side of weakness. Less frequently, brain stem lesions; cervical spinal cord diseases; peripheral nervous system diseases; and other conditions may manifest as hemiplegia. The term hemiparesis (see paresis) refers to mild to moderate weakness involving one side of the body.
179 clinical trials for this condition and its sub-types, 176 tagged with Hemiplegia itself.
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Sub-types of Hemiplegia
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Alternating hemiplegia of childhood 3 trials
3 sub-types
Most studied deeper sub-types
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Can a smart foot device retrain walking after hemiplegia?
Disease control Not yet recruitingThis study tests whether a home-use device called the Motus Nova Foot can improve walking and balance in people aged 12-20 with hemiplegia, a condition where one side of the body is weak. The device moves the ankle and foot while guiding users through video activities, and it tra…
Sponsor: MultiCare Health System Research Institute • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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Can High-Repetition or High-Intensity training boost walking after stroke?
Disease control Not yet recruitingThis trial tests whether adding either high-repetition task-oriented training or high-intensity gait training to standard neurodevelopmental therapy helps people with chronic stroke walk farther and move more easily. Forty-five participants who had a stroke at least six months ag…
Sponsor: Istanbul University - Cerrahpasa • Aim: Disease control
Last updated Jul 26, 2026 00:00 UTC
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Video games could help kids with One-Sided weakness improve hand control and focus
Disease control Not yet recruitingThis study tests whether playing specially designed video games that require both hands and attention can improve hand function, focus, and daily living skills in children aged 7 to 12 with hemiplegia (weakness on one side of the body). Children play Xbox 360 Kinect games that en…
Sponsor: Cairo University • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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Wearable sensors give Real-Time feedback to improve gait in children with hemiplegia
Disease control Not yet recruitingThis trial tests whether a biofeedback system using wearable sensors can improve walking in children aged 7 to 12 with hemiplegia (weakness on one side). Participants wear sensors that provide real-time audio and visual cues while walking on a treadmill, helping them correct abno…
Sponsor: Cairo University • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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VR headset could help stroke survivors relearn daily tasks at home
Disease control Not yet recruitingThis study tests whether a virtual reality (VR) home exercise program can help stroke survivors improve arm and hand function. Forty-eight adults who had a stroke at least 3 months ago will either use a VR headset to practice daily activities at home or receive standard therapy. …
Sponsor: Barron Associates, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Vibrating wearables put stroke walking to the test
Symptom relief Not yet recruitingStroke survivors often walk more slowly and struggle to produce the movements needed for efficient walking. This study tests whether small wearable devices that vibrate during walking can help people with chronic stroke change specific walking movements linked to speed, propulsio…
Sponsor: Geisinger Clinic • Aim: Symptom relief
Last updated Sep 21, 2026 23:00 UTC
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Two therapy approaches go Head-to-Head for Children's arm movement
Symptom relief Not yet recruitingResearchers compare two rehabilitation methods for children with hemiplegic cerebral palsy, a condition that causes muscle tightness and limited arm movement on one side. The trial enrolls 40 children aged 8 to 12 who receive either electromyography biofeedback training, which us…
Sponsor: Cairo University • Aim: Symptom relief
Last updated Sep 18, 2026 00:00 UTC
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Ride-On toys could help kids with cerebral palsy use their weaker arm
Symptom relief Not yet recruitingThis study tests whether using a ride-on toy for 6 weeks can help children with cerebral palsy use their weaker arm and hand more. Ten children will wear a mitten on their stronger hand to encourage using the other hand while driving and playing. Researchers will measure changes …
Sponsor: Grand Valley State University • Aim: Symptom relief
Last updated Sep 13, 2026 00:00 UTC
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Mental math may boost walking in stroke patients
Symptom relief Not yet recruitingThis study tests whether doing simple mental arithmetic before walking can improve gait speed and balance in people who have had a stroke. Seventeen participants will either solve math problems or watch a blank screen before walking. The goal is to see if this 'cognitive priming'…
Sponsor: Lebanese University • Aim: Symptom relief
Last updated Jul 18, 2026 00:00 UTC
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New combo therapy aims to restore hand grip in stroke survivors
Symptom relief Not yet recruitingThis study tests whether combining neuromuscular electrical stimulation with upper limb nerve exercises can improve hand grip strength and range of motion in people who have had a stroke. The trial will include 44 adults who had an ischemic stroke at least 3 months ago and have s…
Sponsor: Riphah International University • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC
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Home workouts boost stroke recovery, new trial to test
Symptom relief Not yet recruitingThis trial tests whether adding a structured home exercise program to regular clinic-based physical therapy helps people aged 40-50 with sub-acute stroke walk better and do daily activities. 72 participants will either get clinic rehab alone or clinic rehab plus home exercises li…
Sponsor: University of Lahore • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Robotic rehab at home could help stroke survivors regain arm function
Symptom relief Not yet recruitingThis study tests whether a personalized robotic telerehabilitation program can help people recover arm movement after a stroke. Seventy participants will use a wearable robotic device with virtual reality exercises at home for 4 weeks, supervised remotely. The goal is to see if t…
Sponsor: University of Campania Luigi Vanvitelli • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Robotic glove gives hope to kids with cerebral palsy
Symptom relief Not yet recruitingThis study compares a robotic glove to standard hand therapy for children with hemiplegic cerebral palsy, a condition where one side of the body is weaker. Seventy children aged 7-15 will receive either robotic or conventional therapy for 8 weeks. Researchers will measure hand fu…
Sponsor: Riphah International University • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Mind over movement: mental rehearsal may smooth arm function after stroke
Symptom relief Not yet recruitingThis study tests whether a single session of a mental practice technique called PETTLEP-based Action Observation and Motor Imagery (AOMI) can immediately improve arm movement in stroke survivors. Participants will either watch and mentally rehearse a reach-to-grasp task or do a c…
Sponsor: Istinye University • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Shocking new combo therapy aims to restore arm movement in stroke survivors
Symptom relief Not yet recruitingThis study tests whether adding functional electrical stimulation (FES) to task-oriented training helps stroke survivors with arm spasticity regain more movement than training alone. All participants receive Botox for spasticity first. The trial will enroll 40 adults who have had…
Sponsor: University of Foggia • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Home robot aims to get stroke patients back on their feet
Symptom relief Not yet recruitingThis study tests a new robotic walking trainer called Rise&Walk InHome that stroke survivors can use at home. Twenty adults who had a stroke 3 months to 5 years ago will either use the device for 30 minutes, 4 times a week plus usual care, or just usual care. The goal is to see i…
Sponsor: Healing Innovations • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Mind over matter: Brain-Wave robot hand may boost stroke recovery
Symptom relief Not yet recruitingThis study compares two types of robotic hand therapy for people with chronic stroke and hand weakness. One group uses a robot that moves when the patient's brain waves show they are imagining the movement, while the other group uses a robot that moves automatically. The goal is …
Sponsor: Seoul National University Bundang Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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New combo therapy aims to restore movement after stroke
Symptom relief Not yet recruitingThis study tests whether combining two therapies—blood flow restriction training (using a cuff to partially restrict blood flow during exercise) and brain stimulation (rTMS)—can improve arm and hand function in people who have weakness on one side after a stroke. 69 adults will b…
Sponsor: The First Affiliated Hospital of Zhengzhou University • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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Video game therapy may improve spine mobility in children with cerebral palsy
Symptom relief Not yet recruitingThis study looks at whether adding exergaming (video games that require movement) to standard NDT-Bobath therapy can improve spinal mobility in children aged 10-15 with cerebral palsy. Forty-two participants will be split into two groups: one doing seated exergaming and the other…
Sponsor: Wroclaw University of Health and Sport Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Shoes that could change how stroke survivors walk
Symptom relief Not yet recruitingThis study looks at whether custom-made shoes can improve walking quality in people who have had a stroke and still have trouble walking due to muscle tightness and foot dragging. About 58 adults who had a stroke at least 6 months ago will wear adapted shoes and be tested on how …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Robot walking training: free pelvis may help stroke survivors walk better
Symptom relief Not yet recruitingThis study tests whether allowing the pelvis to move freely during robot-assisted walking training helps stroke survivors walk better, improve balance, and reduce fear of falling. About 36 adults who had a stroke at least 6 months ago will receive either pelvic-free or pelvic-res…
Sponsor: Meltem Gunes Akinci • Aim: Symptom relief
Last updated Jun 27, 2026 08:14 UTC
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Shock therapy: can zapping nerves ease Post-Stroke shoulder pain?
Symptom relief Not yet recruitingThis study tests whether adding neuromuscular electrical stimulation (NMES) to standard TENS therapy provides extra relief for shoulder pain after a stroke. Forty adults with hemiplegic shoulder pain will receive either TENS alone or TENS plus NMES, alongside their usual rehab. T…
Sponsor: Medical Park Bursa Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Could a simple tape boost stroke recovery?
Symptom relief Not yet recruitingThis study looks at whether adding posture-oriented kinesio taping to standard rehab helps stroke patients improve their balance, coordination, and daily activities. Sixty adults who had a stroke at least one month ago will be randomly assigned to get either the tape plus rehab o…
Sponsor: Bursa City Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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Robot therapy may give kids with cerebral palsy a stronger grip
Symptom relief Not yet recruitingThis study will test whether robotic-assisted therapy can improve hand function, grip strength, and wrist position sense in 32 children aged 6-9 with hemiplegic cerebral palsy. Participants will use a robotic device to perform repetitive, goal-oriented hand exercises. The goal is…
Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Spinal zaps plus treadmill training may help TBI survivors walk again
Symptom relief Not yet recruitingThis study will test whether a mild electrical stimulation applied to the lower back, combined with walking exercises, can improve mobility and balance in people with traumatic brain injury (TBI) who have weakness on one side. Thirty adults with a non-penetrating TBI at least two…
Sponsor: Kessler Foundation • Aim: Symptom relief
Last updated Jun 26, 2026 13:09 UTC
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Could digital skills help stroke survivors rejoin community life?
Knowledge-focused Not yet recruitingThis study investigates whether digital health literacy—the ability to find and use health information online—is linked to social participation in adults with hemiplegia after a stroke. Researchers will assess 250 participants using questionnaires to measure digital health litera…
Sponsor: Afyonkarahisar Health Sciences University • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
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Intensive hand therapy shows promise for children with one-sided cerebral palsy
Knowledge-focused Not yet recruitingThis study looks back at children with unilateral cerebral palsy (weakness on one side) who took part in intensive therapy programs called COLHEMI or Mini-COLHEMI. These programs provide many hours of focused hand and arm training over two weeks. Researchers want to understand ho…
Sponsor: Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
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New study probes muscle tone and balance in kids with spastic hemiplegia
Knowledge-focused Not yet recruitingThis study will look at how muscle stiffness and tone relate to balance in children aged 6 to 12 with spastic hemiplegia, a condition where one side of the body is tight and weak. Researchers will use a handheld device to measure muscle properties and a balance system to test sta…
Sponsor: South Valley University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:10 UTC
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New tool could help doctors spot muscle problems after stroke
Knowledge-focused Not yet recruitingThis study checks if a tool called the Hypertonia Assessment Tool (HAT) can correctly identify different types of muscle tightness in adults who have had a stroke. The tool was already tested in children with cerebral palsy, but not in adults after stroke. Researchers will test 6…
Sponsor: Fatih Sultan Mehmet Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC