Hemiplegia

This trial compares two rehabilitation approaches—constraint-induced movement therapy (CIMT) and task-oriented training (TOT)—to see which better improves hand function in people recovering from a stroke. About 48 adults aged 45–65 who had a stroke more than three months ago will…

This study tests whether giving stroke patients real-time feedback on muscle activity—either through a visual display or sounds—can improve balance, walking, and daily independence when added to standard physical therapy. The trial enrolls adults aged 20-30 who have had a hemiple…

This study tests an implanted electrical stimulator to improve walking in people who have had a stroke. Six participants will first be screened, then receive the implant and use it at home. Researchers will compare advanced control settings to a simple trigger to see which works …

This trial tests whether adding a robotic glove to mirror therapy can improve arm and hand function in children with hemiparetic cerebral palsy. Participants will receive either robot-assisted or conventional mirror therapy alongside standard neurodevelopmental treatment for six …

This pilot study tests whether a home-based training program using joystick-operated ride-on toys can help children aged 3-8 with hemiplegia improve arm function. Children will use their affected arm to drive the toy through playful challenges, compared to a creative upper extrem…

This study compares a special exercise program called Coordinative Locomotor Training (CLT) to regular physiotherapy for children aged 8 to 12 with spastic hemiplegic cerebral palsy, a condition that causes stiffness on one side of the body. CLT uses running and skating movements…

This study tests whether combining neuromuscular electrical stimulation (NEMS) with voluntary muscle contraction can improve ankle function in people with chronic stroke. Twenty-five participants will either receive conventional physiotherapy or NEMS plus active dorsiflexion exer…

This study tests a device called GaitBetter that combines treadmill walking with cognitive training (like thinking tasks) to help stroke survivors improve their walking and balance. About 76 people who had a stroke (either within 8 weeks or more than 6 months ago) will use the de…

This study tests two different therapies—digital mirror therapy and action observation therapy—to see which better improves arm movement and grip strength in children with hemiplegia (one-sided weakness). Forty-five children aged 6 to 8 will participate. The goal is to find a sim…

This study looks at whether using a passive kinesiotherapy device on the legs for 30 minutes can immediately reduce muscle stiffness (spasticity) and improve walking in people with conditions like cerebral palsy, stroke-related weakness, or spinal cord issues. About 80 participan…

This study tests whether a portable shoulder exoskeleton can help people who had a stroke move their arm and hand better. About 30 participants will perform tasks like reaching and picking up objects with and without the device. The goal is to see if the exoskeleton improves dail…

This study looks at the cost and benefits of a two-week day camp for children with mild to moderate arm weakness (hemiparesis) from cerebral palsy or brain injury. In the first week, children wear a constraint on their stronger arm to encourage use of the weaker arm, followed by …

This study looks at whether adding tolperison to botulinum toxin injections helps reduce muscle stiffness and nerve pain in stroke survivors. About 40 adults with spastic hemiplegia (one-sided paralysis) will be followed. Researchers will measure spasticity and walking speed to s…

This study tests whether mirror therapy can help people who have had a stroke regain movement and reduce pain in a weak arm. Participants do arm exercises while watching the reflection of their good arm, which tricks the brain into thinking the weak arm is moving. The trial invol…

This study tests whether adding a mild electrical stimulation to the neck muscles can help people who recently had a stroke and now have trouble swallowing. Forty participants will receive either standard swallowing therapy or therapy plus electrical stimulation. The goal is to s…

This study compares traditional balance exercises with video game-based exergaming (using Nintendo Switch Ring Fit Adventure) in stroke survivors with hemiplegia. Thirty participants will be split into two groups, both receiving standard physiotherapy plus either balance exercise…

This study tests a device called the Neuromechanical Gait Assist (NMGA) that combines a powered knee brace with muscle stimulation to help people who have difficulty walking after a stroke. Five veterans with leg weakness and a stiff-legged gait will use the device in a lab while…

This study looks at how a stroke affects the jaw joint and chewing muscles. Researchers will use ultrasound to measure jaw structures in 70 stroke survivors and see if these measurements relate to their recovery. The goal is to better understand jaw problems after a stroke, which…

This study is observing up to 198 people with rapid-onset dystonia-parkinsonism (RDP) or related genetic mutations. Researchers aim to identify affected individuals, document how common the disease is, and track its progression over time. Participants undergo assessments of sympt…

This study looks at whether shoulder problems make balance worse for people who have had a stroke and have weakness on one side. Researchers will compare balance in 100 stroke survivors—some with shoulder pain and some without. The goal is to understand if treating shoulder issue…