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Hemiplegia
MONDO:0001170Severe or complete loss of motor function on one side of the body. This condition is usually caused by brain diseases that are localized to the cerebral hemisphere opposite to the side of weakness. Less frequently, brain stem lesions; cervical spinal cord diseases; peripheral nervous system diseases; and other conditions may manifest as hemiplegia. The term hemiparesis (see paresis) refers to mild to moderate weakness involving one side of the body.
155 clinical trials for this condition and its sub-types.
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Broader categories
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Botulinum injection trial for arm spasticity halted early
Disease control TerminatedThis study tested whether injections of MYOBLOC (botulinum toxin type B) can safely reduce muscle tightness in the arm and hand of adults with spasticity caused by stroke, brain injury, multiple sclerosis, or other conditions. The trial planned to enroll about 300 participants bu…
Phase: PHASE2, PHASE3 • Sponsor: Solstice Neurosciences, LLC, a subsidiary of MDD US Operations, LLC • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Botulinum toxin injection aimed at easing leg spasticity after stroke or injury
Symptom relief TerminatedThis study tested whether MYOBLOC, a botulinum toxin injection, can safely reduce muscle stiffness in the lower leg of adults with spasticity caused by stroke, brain injury, or spinal cord injury. About 40 participants received either a low or high dose of MYOBLOC or a placebo in…
Phase: PHASE2, PHASE3 • Sponsor: Solstice Neurosciences, LLC, a subsidiary of MDD US Operations, LLC • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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New ankle brace aims to fix foot drop after stroke
Symptom relief TerminatedThis study tested a brace called CALIGALOC designed to correct foot drop (ankle varus) in people with hemiparesis after a stroke or other brain injury. The goal was to see if wearing the brace for 15 days improved walking speed and balance. Only 5 people took part, and the study …
Phase: NA • Sponsor: University Hospital, Lille • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Magnetic zaps to the brain aim to restore arm movement in stroke survivors
Symptom relief TerminatedThis study tested whether a magnetic device (rTMS) placed on the scalp could help people who had a stroke regain movement in their arm. The trial planned to include 60 adults with recent ischemic stroke. However, the study was terminated early, so the results are not complete.
Phase: NA • Sponsor: Seoul National University Bundang Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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Brain zaps tested for stroke arm recovery – but study stalls
Knowledge-focused TerminatedThis study tested whether a single session of magnetic brain stimulation (called rTMS) over a specific brain area could improve pointing movements in people who had a stroke. Only one person took part, and the study was stopped early. The goal was to see if the stimulation could …
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC