New shot aims to loosen stiff legs after stroke or injury

NCT ID NCT04099667

Terminated Symptom relief Sponsor: Solstice Neurosciences, LLC, a subsidiary of MDD US Operations, LLC Source: ClinicalTrials.gov ↗

First seen May 26, 2026 · Last updated Jun 16, 2026 · Updated 5 times

Summary

This study tested a single injection of MYOBLOC in 40 adults with leg muscle stiffness (spasticity) caused by stroke, brain injury, or spinal cord injury. The goal was to see if it safely reduces stiffness and improves movement compared to a placebo. The trial was stopped early, so results are limited.

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Contacts and locations

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Locations

Centrum Medyczne Linden

Krakow, 31-721, Poland
Coastal Neurology

Port Royal, South Carolina, 29935, United States
Idaho Physical Medicine and Rehabilitation

Boise, Idaho, 83706, United States
National Institute of Medical Rehabilitation

Budapest, H-1121, Hungary
Niepubliczny Zaklad Opieki Zdrowotnej (NZOZ) Neuromed

Lubin, 20-604, Poland
Rancho Research Institute

Downey, California, 90242, United States
Specjalistyczna Praktyka Lekarska

Katowice, 40-097, Poland
Specjalistyczne Gabinety

Krakow, 30-539, Poland
University of Texas Southwestern Medical Center

Dallas, Texas, 75390, United States

Conditions

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SPASTICITY