Can freezing nerves ease chronic pain? yale study aims to find out
NCT ID NCT07639060
First seen Jun 17, 2026 · Last updated Jun 19, 2026 · Updated 1 time
Summary
This study will follow 80 people with chronic pain who are receiving cryoneurolysis, a procedure that uses cold to temporarily freeze nerves and block pain signals. Researchers will track pain levels, disability, and healthcare use for 12 months after treatment. The goal is to see if this approach provides meaningful, lasting relief for conditions like back pain, arthritis, and nerve pain.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cryoneurolysis (a procedure that uses extreme cold to temporarily freeze nerves and reduce pain)
What this could lead to
If successful, this could show that cryoneurolysis provides meaningful, lasting pain relief for people with various chronic pain conditions.
What could go wrong
This is a small, early-stage observational study with no comparison group, so results may not apply to everyone. Pain relief may be temporary or not work for all participants.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.