PERIPHERAL NEUROPATHY

This study tests whether taking polyunsaturated fatty acid supplements can prevent nerve damage in the hands and feet of people with colorectal cancer who receive oxaliplatin chemotherapy after surgery. About 120 participants will be randomly assigned to receive the supplement or…

This study tests whether fenofibrate, a medicine usually used for high cholesterol, can reduce nerve damage (peripheral neuropathy) caused by a common chemotherapy combination for multiple myeloma. About 44 newly diagnosed patients will receive either standard chemo alone or chem…

This study looks at whether turning a nerve stimulator on and off (30 seconds on, 90 seconds off) works as well as leaving it on all the time for people with chronic pain from conditions like CRPS, radiculopathy, or peripheral neuropathy. About 30 adults who have had a spinal ner…

This study is testing whether a device called Replexa+, which uses shortwave diathermy, can improve blood flow in the lower legs and feet of veterans with peripheral artery disease (PAD) and peripheral neuropathy. Ten participants will use the device twice daily for three months.…

This study tests a new magnetic stimulation method (AtMS) to reduce nerve pain caused by injury or surgery in veterans and active-duty military. 180 participants will receive either AtMS, a fixed stimulation, or a sham treatment over 16 weeks. Researchers will measure pain levels…

This study tests whether Tai Chi, alpha-lipoic acid supplements, and acupuncture can help reduce nerve pain caused by chemotherapy in people who have had gastrointestinal cancer. About 60 adults who finished chemo at least three months ago and still have numbness and tingling wil…

This study tests a treatment called Scrambler therapy for nerve pain caused by chemotherapy in teens and young adults (ages 15-39) who have finished active cancer treatment. The therapy uses mild electrical signals to 'scramble' pain messages to the brain. Researchers will compar…

This study looks at whether a hormone called amylin, which is higher in people with type 2 diabetes, is linked to nerve damage (peripheral neuropathy). Researchers will collect blood and small skin samples from 40 participants to measure amylin levels and compare them to nerve fu…

This study looks at whether generative AI can help doctors better diagnose complications of rheumatoid arthritis (RA), such as lung disease or heart problems. Researchers will use AI to analyze patient records and suggest possible complications, then see if doctors find these sug…

This study looks at how nerves work in people who develop nerve damage from the chemotherapy drug cisplatin. Researchers will use a special test to measure nerve signals in 60 adults starting cisplatin treatment. The goal is to better understand the nerve damage and find early wa…

This study looks at whether ultrasound can detect nerve changes in people with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Researchers will compare ultrasound images with standard nerve tests to see if ultrasound helps diagn…

This study aims to improve how doctors observe nerves and muscles using ultrasound, a safe imaging technique. Researchers will collect normal measurements from healthy adults and compare them to people with neuromuscular disorders like muscular dystrophy or peripheral neuropathy.…

This study follows 20 people with a rare nerve disease called CMT4J to learn how the condition progresses. Participants of any age will be checked once a year for two years. The goal is to better understand the disease, not to test a treatment.

This study checks if special sensors can accurately measure the forces inside a carbon-fiber leg brace. Researchers will test the brace on healthy adults, people who use braces regularly, and those with nerve damage in their feet. The goal is to improve how braces are designed an…