Could a hormone be the hidden cause of diabetic nerve pain?
NCT ID NCT03481283
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is investigating whether the hormone amylin, which is elevated in type 2 diabetes, is linked to peripheral neuropathy (nerve damage). Researchers will collect blood and skin samples from 40 adults with type 2 diabetes and mild-to-severe neuropathy. They will measure amylin levels in red blood cells and blood vessel walls, then compare them to nerve function and pain sensitivity. The goal is to see if higher amylin levels are associated with worse nerve symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If a link is found, this could point toward new ways to detect or treat diabetic nerve damage.
What could go wrong
This is a small, early observational study. It only looks for a correlation, not a cause, and may not lead to any treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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UK Robert Straus Behavioral Science Laboratory
ACTIVE_NOT_RECRUITINGLexington, Kentucky, 40508, United States
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University of Kentucky - Kentucky Neuroscience Institute
RECRUITINGLexington, Kentucky, 40536, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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