Fish oil may shield cancer patients from chemo nerve pain

NCT ID NCT05404230

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking fish oil supplements can prevent nerve damage in the hands and feet caused by oxaliplatin chemotherapy in colorectal cancer patients. 120 participants will receive either fish oil or corn oil (placebo) during their treatment. The goal is to see if fish oil reduces the number of patients who develop painful nerve symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fish oil (polyunsaturated fatty acids)

What this could lead to

If it works, this could provide a simple, low-cost way to prevent painful nerve damage from oxaliplatin chemotherapy.

What could go wrong

This is a small, early-stage trial with only 120 participants. The benefit may be small or not work at all, and fish oil supplements can cause mild side effects like fishy aftertaste or stomach upset.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm peripheral nervous system disorder peripheral neuropathy chemotherapy-induced neuropathy prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Oncology

    RECRUITING

    Sønderborg, Denmark

    Contact

  • Department of Oncology, AAUH

    RECRUITING

    Aalborg, Denmark

    Contact

  • Department of Oncology, AUH

    RECRUITING

    Aarhus, Denmark

    Contact

  • Department of Oncology, Vejle Hospital

    RECRUITING

    Vejle, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••