Dyspepsia
MONDO:0002268An uncomfortable, often painful feeling in the stomach, resulting from impaired digestion. Symptoms include burning stomach pain, bloating, heartburn, nausea, and vomiting. Causes include gastritis, gastric ulcer, gastroesophageal reflux disease, pancreatic disease, and gallbladder disease.
Also known as: dyspepsia, indigestion, indigestion
86 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Herbal combo boosts h. pylori treatment, study finds
Disease control CompletedThis study tested whether adding a traditional Chinese herbal formula (Banxiaxiexin decoction) to standard antibiotics can better treat H. pylori infection and related indigestion. 104 adults with both conditions took either the herbal combo or standard therapy for 14 days. The m…
Phase: PHASE3 • Sponsor: Nanjing First Hospital, Nanjing Medical University • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Stomach bacteria transplant shows promise for indigestion relief
Disease control CompletedThis study tested whether transplanting specific stomach bacteria (probiotics) could relieve symptoms of functional dyspepsia, a common digestive disorder. 74 adults with indigestion but no H. pylori infection received either the probiotic or a placebo. The main goal was to see i…
Phase: NA • Sponsor: Nanfang Hospital, Southern Medical University • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Simple drug may cut infection risk after major gut surgery
Disease control CompletedThis study tested whether tranexamic acid, a drug that helps blood clot, can lower the chance of infection after gastrointestinal surgery. Over 3,300 adults at higher risk for complications took part. The goal was to see if the drug reduces surgical site infections compared to a …
Phase: PHASE4 • Sponsor: Bayside Health • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Swallow a magnet: new capsule could spot stomach disorders
Diagnosis CompletedThis study tested a special capsule with a magnet inside that doctors can control from outside the body. The capsule takes pictures of the stomach to see how it moves and digests food. Researchers wanted to see if this device could help diagnose conditions like gastroparesis and …
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Diagnosis
Last updated Jun 27, 2026 12:24 UTC
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Magnetic stomach test could replace X-Rays for gut diagnosis
Diagnosis CompletedThis study tested a new, noninvasive technique called magnetogastrogram (MGG) to measure the stomach's electrical activity without radiation. Researchers studied 22 people, including those with diabetes, gastroparesis, and other stomach conditions, to see if the test can tell nor…
Phase: EARLY_PHASE1 • Sponsor: Vanderbilt University Medical Center • Aim: Diagnosis
Last updated Jun 27, 2026 12:23 UTC
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Ear zaps for tummy troubles? new study tests nerve stimulation for stomach pain
Symptom relief CompletedThis study tests whether a mild electrical pulse to the ear (taVNS) can change how the brain and stomach interact in people with chronic indigestion or gastroparesis. Researchers will use brain scans and stomach electrical readings to see if the stimulation helps. The goal is to …
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jul 04, 2026 00:00 UTC
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Can chair yoga soothe stomach troubles? new study aims to find out
Symptom relief CompletedThis study tests whether a chair-based yoga program is practical and acceptable for people with functional dyspepsia or gastroparesis—conditions that cause nausea, vomiting, and stomach pain. Ten adults will attend two one-hour yoga sessions and practice at home. Researchers will…
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Jul 01, 2026 00:00 UTC
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Can an online wellness program ease anxiety in chronic disease?
Symptom relief CompletedThis study tested a 12-week online mind-body program for adults with chronic conditions like heart failure, cancer, and liver disease. The program included mindful movement, meditation, breathwork, and coping skills. Researchers measured changes in anxiety, depression, fatigue, a…
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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New syrup shows promise for soothing stubborn heartburn
Symptom relief CompletedThis study tested a new syrup, called Fibroin Syrup, to see if it is safe and can help reduce symptoms of gastroesophageal reflux disease (GERD), like heartburn and regurgitation. The study included 47 adults with non-erosive reflux disease (NERD) who had symptoms for at least 8 …
Phase: NA • Sponsor: Rose Pharma SA • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Which diet soothes stomach pain better? new study tests two options
Symptom relief CompletedThis study looked at 60 people with a common stomach condition called functional dyspepsia, which causes pain and fullness after meals. Participants were split into two groups: one followed standard advice (small meals, avoid fatty/spicy foods), and the other tried a low FODMAP d…
Phase: NA • Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Could one pill a day replace three for stomach upset?
Symptom relief CompletedThis study tested if taking itopride once daily works as well as taking it three times a day for people with ongoing stomach discomfort (functional dyspepsia). Over 500 adults participated, and researchers measured symptom changes over 8 weeks. The goal was to see if a simpler do…
Phase: PHASE3 • Sponsor: Abbott • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Could a 'Stomach Pacemaker' stop Kids' chronic nausea?
Symptom relief CompletedThis study tested whether a device that sends small electrical pulses to the stomach can help children with severe, long-lasting nausea and vomiting. Thirty kids who hadn't gotten better with standard treatments took part. Each child had a temporary pacing lead placed through a t…
Phase: NA • Sponsor: Nationwide Children's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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New drug eases stomach pain in clinical trial
Symptom relief CompletedThis study tested a drug called DLBS2411 in 106 adults with functional dyspepsia, a condition causing stomach pain and fullness without a clear cause. Participants took either the drug or a placebo twice daily for 4 weeks. The goal was to see if the drug improves quality of life …
Phase: PHASE3 • Sponsor: Dexa Medica Group • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Could a common amino acid soothe stomach pain?
Symptom relief CompletedThis small study tested whether taking glutamine powder three times a day can reduce stomach symptoms and improve gut barrier health in people with functional dyspepsia (chronic indigestion without a clear cause). Twelve participants were randomly assigned to receive either gluta…
Phase: PHASE1, PHASE2 • Sponsor: David J. Cangemi • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Audio hypnotherapy could ease Kids' tummy troubles without meds
Symptom relief CompletedThis study tested if listening to hypnotherapy audio files can help children and teens with stomach pain and bowel problems linked to stress. 32 participants used the audio treatment at home. The goal was to see if this approach is practical and effective, potentially offering a …
Phase: NA • Sponsor: Karolinska Institutet • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Herbal tea combo tested for stomach relief
Symptom relief CompletedThis study tested whether taking artemisia and green tea extracts for 8 weeks can improve stomach health in adults with functional dyspepsia (indigestion without a clear cause). 100 participants were randomly assigned to receive the extracts or a placebo. The main goal was to see…
Phase: NA • Sponsor: Pusan National University Yangsan Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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No-Pill bloating fix? Video-Guided breathing shows promise
Symptom relief CompletedThis study tested a non-instrumental biofeedback technique to help people with irritable bowel syndrome or dyspepsia who experience visible abdominal bloating after meals. 41 participants were taught to control their abdominal and chest muscles using a video guide, then practiced…
Phase: NA • Sponsor: Hospital Universitari Vall d'Hebron Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Fruit salt fights indigestion in minutes – new study
Symptom relief CompletedThis completed Phase 3 trial tested whether ENO Lime, a fruit salt powder, can quickly ease symptoms of indigestion, acidity, and nausea. Forty adults with recent symptoms took a single dose, and their discomfort was measured before and 15 minutes after. The study aimed to see if…
Phase: PHASE3 • Sponsor: HALEON • Aim: Symptom relief
Last updated Jun 26, 2026 18:37 UTC
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New supplement shows promise for soothing heartburn
Symptom relief CompletedThis study tested whether a liquid dietary supplement called Anvitra Gastric Suspension can reduce heartburn, regurgitation, and indigestion in people with GERD. Twenty-seven adults took the supplement three times daily for 14 days. Researchers measured symptom changes using a st…
Phase: NA • Sponsor: Haiphong University of Medicine and Pharmacy • Aim: Symptom relief
Last updated Jun 26, 2026 17:08 UTC
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Stomach pain mystery: why do some patients stay sick despite treatment?
Knowledge-focused CompletedThis study followed 300 adults with functional dyspepsia (chronic stomach discomfort) who were taking standard medications like acid reducers or antidepressants. The goal was to see which factors—such as anxiety or sleep problems—might predict whether symptoms improve after 6 mon…
Sponsor: Air Force Military Medical University, China • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Stomach Staple-Line fix: small study tests if omentopexy eases Post-Surgery symptoms
Knowledge-focused CompletedThis study tested whether adding omentopexy — stitching the omentum to the stomach — during sleeve gastrectomy changes stomach shape and emptying. Thirty-six adults having weight-loss surgery were randomly assigned to get the extra stitch or not. Researchers measured stomach angl…
Phase: NA • Sponsor: Ankara University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Brain zap tunes heart and gut: new hope for depression?
Knowledge-focused CompletedThis completed study tested whether noninvasive brain stimulation can be personalized by measuring heart rate responses. Researchers mapped the scalp to find the best spot for stimulation in 34 healthy participants and people with depression, anxiety, and gut issues. They compare…
Phase: NA • Sponsor: University of Bern • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Could a special diet help IBS patients with flexible joints?
Knowledge-focused CompletedThis study looked at nearly 500 people with stomach and bowel problems to see if a low-FODMAP diet helps reduce symptoms. Researchers also checked for joint hypermobility (very flexible joints) and how the gut microbiome might be linked. The goal is to better understand who benef…
Phase: NA • Sponsor: University of Zurich • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC