Could a common amino acid soothe stomach pain?

NCT ID NCT05655819

Completed Symptom relief Sponsor: David J. Cangemi Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This small study tested whether taking glutamine powder three times a day can reduce stomach symptoms and improve gut barrier health in people with functional dyspepsia (chronic indigestion without a clear cause). Twelve participants were randomly assigned to receive either glutamine or a placebo for a set period. Researchers measured symptom changes using questionnaires and a urine test for intestinal permeability.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: glutamine
What this could lead to: If it works, this could point toward a simple, low-cost supplement to help manage functional dyspepsia symptoms.
What could go wrong: This is a very small, early-phase trial with only 12 participants. Results may not apply to everyone, and the benefit over placebo is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dyspepsia functional gastric disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FUNCTIONAL DYSPEPSIA

Contacts and locations

Locations

Torsak Vimoktayon

Jacksonville, Florida, 32258, United States

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