Stomach pain mystery: why do some patients stay sick despite treatment?

NCT ID NCT05513040

Completed Knowledge-focused Sponsor: Air Force Military Medical University, China Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study followed 300 adults with functional dyspepsia (chronic stomach discomfort) who were taking standard medications like acid reducers or antidepressants. The goal was to see which factors—such as anxiety or sleep problems—might predict whether symptoms improve after 6 months. Researchers hope to better understand why 20-50% of patients don't get relief from current treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors identify which patients with functional dyspepsia are less likely to improve with standard medications, allowing for more personalized treatment plans.
What could go wrong: This is an observational study, not a test of a new treatment. It only looks at existing medications and cannot prove cause and effect. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dyspepsia functional gastric disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FUNCTIONAL DYSPEPSIA

Contacts and locations

Locations

Lanzhou University Second Hospital

Lanzhou, Gansu, China
The Second Affiliated Hospital of Xi'an Jiaotong University

Xi'an, Shaanxi, 710032, China
Xijing 986 Hospita

Xi'an, Shaanxi, 710032, China
Xijing Hospital of Digestive Diseases

Xi'an, Shaanxi, 710032, China

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