Disease of bone structure

This study tested a special bone graft material (MatriBONE mixed with the patient's own bone marrow) for spinal fusion surgery in people with painful degenerative back problems. The goal was to see how well the bones fused together after 12 months. However, the trial was stopped …

This study tested a device called the Braive Growth Modulation System in 10 children with scoliosis (curved spine). The goal was to see if it could safely correct the curve as the child grows. The study was stopped early, so results are limited.

This study looked at whether wearing a back brace can stop spine curves from getting worse in teens with scoliosis. About 383 teens with mild to moderate curves were either assigned to wear a brace for at least 18 hours a day or just be observed. The goal was to see if bracing le…

This study aimed to find the ideal dose of a spinal pain medicine (hydromorphone) for children undergoing back surgery for scoliosis. Researchers tested several doses in 31 patients to balance good pain control with fewer side effects. The trial was stopped early, so the results …

This study looked at whether giving teenagers a numbing medicine (lidocaine) through an IV during and after spine surgery could lower their need for strong painkillers (opioids) and help them recover faster. The trial planned to include 15 teens aged 12-18 with scoliosis, but it …

This study looked at two different combinations of anesthesia medicines given through an IV to teenagers having surgery for scoliosis. The goal was to see if one combination leads to less pain and less need for opioid painkillers after surgery. The study was small and ended early…

This study was a registry that planned to follow 234 adults undergoing spine fusion surgery for conditions like spinal stenosis and degenerative disc disease. Researchers aimed to compare different surgical techniques and track long-term outcomes, including pain, function, and wh…

This early study tested an optical 3D scanner designed to help surgeons align spine anatomy during operations. The goal was to see if the scanner could accurately match a patient's spine to pre-surgery MRI or CT scans. Only 2 participants were enrolled before the study was termin…

This study tested a new 3D scanning device that aims to help surgeons match a patient's spine bones to their MRI or CT scans during surgery. The goal was to see if the scanner could accurately and consistently map the spine to improve surgical precision. Only one person took part…

This study collected bone, cartilage, skin, and fat tissue from 50 patients undergoing surgery at Children's National Medical Center. The goal was to grow cells from these tissues in the lab and analyze them to better understand bone and connective tissue diseases. The study was …