Study seeks sweet spot for painkiller dose in Children's spine surgery
NCT ID NCT05552443
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study aimed to find the ideal dose of a spinal pain medicine (hydromorphone) for children undergoing back surgery for scoliosis. Researchers tested several doses in 31 patients to balance good pain control with fewer side effects. The trial was stopped early, so the results are not definitive.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hydromorphone
What this could lead to
If successful, this could help doctors choose the safest, most effective dose of hydromorphone for pain control in children after spine surgery.
What could go wrong
The trial was terminated early with only 31 participants, so results are limited. It only tested one type of surgery and excluded children with prior pain or opioid use, so findings may not apply broadly.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Mayo Clinic Rochester
Rochester, Minnesota, 55905, United States