Study seeks sweet spot for painkiller dose in Children's spine surgery

NCT ID NCT05552443

Terminated Symptom relief Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study aimed to find the ideal dose of a spinal pain medicine (hydromorphone) for children undergoing back surgery for scoliosis. Researchers tested several doses in 31 patients to balance good pain control with fewer side effects. The trial was stopped early, so the results are not definitive.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: hydromorphone
What this could lead to: If successful, this could help doctors choose the safest, most effective dose of hydromorphone for pain control in children after spine surgery.
What could go wrong: The trial was terminated early with only 31 participants, so results are limited. It only tested one type of surgery and excluded children with prior pain or opioid use, so findings may not apply broadly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

agnosia idiopathic scoliosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PAIN CONTROL

Contacts and locations

Locations

Mayo Clinic Rochester

Rochester, Minnesota, 55905, United States

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