New study tests safer pain control for teens after spine surgery

NCT ID NCT06096181

Terminated Symptom relief Sponsor: Cedars-Sinai Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at two different combinations of anesthesia medicines given through an IV to teenagers having surgery for scoliosis. The goal was to see if one combination leads to less pain and less need for opioid painkillers after surgery. The study was small and ended early, so the findings are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Propofol, Remifentanil, and Dexmedetomidine
What this could lead to: If it works, this could point toward a better way to manage pain after scoliosis surgery in teens, reducing the need for strong painkillers.
What could go wrong: This is a small, early-phase study that was terminated early, so results may not be reliable. Dexmedetomidine is not FDA-approved for children, and the study may not show a clear benefit.

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Conditions

The condition(s) this trial relates to.

adolescent idiopathic scoliosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADOLESCENT IDIOPATHIC SCOLIOSIS DEXMEDETOMIDINE MULTIMODAL ANALGESIA OPIOID INDUCED HYPERALGESIA POSTERIOR SPINAL FUSION REMIFENTANIL

New study tests safer pain control for teens after spine surgery

Summary

What this could mean

Get notified about this study

Conditions

As listed by the trial registrant

Contacts and locations

Locations

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