New study tests safer pain control for teens after spine surgery

NCT ID NCT06096181

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at two different combinations of anesthesia medicines given through an IV to teenagers having surgery for scoliosis. The goal was to see if one combination leads to less pain and less need for opioid painkillers after surgery. The study was small and ended early, so the findings are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Propofol, Remifentanil, and Dexmedetomidine

What this could lead to

If it works, this could point toward a better way to manage pain after scoliosis surgery in teens, reducing the need for strong painkillers.

What could go wrong

This is a small, early-phase study that was terminated early, so results may not be reliable. Dexmedetomidine is not FDA-approved for children, and the study may not show a clear benefit.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

adolescent idiopathic scoliosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States