ADOLESCENT IDIOPATHIC SCOLIOSIS

This study tests whether giving iron supplements to teens with iron deficiency before scoliosis surgery can reduce the need for blood transfusions and improve thinking and physical recovery afterward. About 275 participants aged 10-26 will receive either iron pills or a placebo f…

This study tests whether injecting Dysport (a muscle relaxant similar to Botox) into back muscles, combined with wearing a brace, can improve spine curvature in teens aged 10-16 with mild to moderate scoliosis. About 90 participants will receive either Dysport or a placebo, plus …

This study tests a new 3D-printed scoliosis brace that has flexible sections to improve comfort. Five teens aged 8-18 who already wear a standard brace will try the new brace and compare how it feels during everyday tasks like sitting and putting on shoes. The goal is to see if a…

This study looks at how giving dexamethasone (a steroid) through a shot near the spine or through an IV affects pain and inflammation in children aged 10-18 having scoliosis surgery. It also tests different strengths of local anesthetic. The goal is to find the best approach to r…

This study tests whether an erector spinae plane block (ESPB) — an injection of the anesthetic ropivacaine into back muscles — can reduce pain and the need for pain medication in children undergoing posterior spinal fusion for scoliosis. About 42 children with adolescent idiopath…

This study compares two types of anesthesia for teenagers having surgery to correct scoliosis (curved spine). One group gets standard opioid-based pain medicine, the other gets a non-opioid approach using dexmedetomidine. The goal is to see if opioid-free anesthesia can control p…

This pilot study tests a new type of brace that uses MRI scans to guide real-time adjustments for teens with mild scoliosis. The brace has air-filled pads that can be inflated or deflated to apply the right amount of pressure. Researchers want to see if this approach can quickly …

This study compares two numbing medicines injected during scoliosis surgery to see which one better controls pain and reduces the need for strong opioid painkillers. About 128 teens aged 10 to 17 will be randomly assigned to receive either a long-acting numbing drug (liposomal bu…

This study tests whether supervised home exercise sessions via video can improve physical fitness in teens with scoliosis. Seventy non-athletic adolescents will be split into two groups: one gets live video coaching, the other follows a self-guided exercise plan. The main goal is…

This pilot study uses a special MRI scan to measure water movement in the spinal discs of children aged 8 to 16, both with and without scoliosis. The goal is to learn more about how the discs behave in scoliosis, which may help explain why the condition develops. The study involv…

This study is a registry that collects information from children and teens up to age 21 who are having spine surgery with robotic and navigation tools. The goal is to track how accurately screws are placed and how much radiation patients and surgeons receive. No new treatment is …

This study tests a wearable device and smartphone app that track how often and how tightly teens with scoliosis wear their brace. Researchers want to see if giving patients and their families real-time feedback on brace use improves compliance. About 87 adolescents with scoliosis…

This study looks at whether 3D dynamic models can help surgeons make better decisions when treating adolescent idiopathic scoliosis. Researchers will collect data from 100 patients aged 10-35 who are scheduled for surgery. The goal is to identify key 3D parameters that could impr…