Iron pills before scoliosis surgery may cut transfusions and boost recovery

NCT ID NCT06042699

Recruiting now Disease control Sponsor: Columbia University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving iron supplements to teens with iron deficiency before scoliosis surgery can reduce the need for blood transfusions and improve thinking and physical recovery afterward. About 275 participants aged 10-26 will receive either iron pills or a placebo for 6-24 weeks before their spinal fusion surgery. The goal is to see if correcting iron deficiency makes surgery safer and recovery smoother.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: oral ferrous sulfate (iron supplement)
What this could lead to: If it works, this could show that a simple iron supplement before surgery reduces the need for blood transfusions and helps teens recover better after scoliosis surgery.
What could go wrong: This is a relatively small, early-stage trial. Iron supplements may not significantly change outcomes, and some participants may experience mild side effects like stomach upset.

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Conditions

The condition(s) this trial relates to.

adolescent idiopathic scoliosis anemia Iron Deficiencies Postoperative Cognitive Complications Postoperative Complications scoliosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADOLESCENT IDIOPATHIC SCOLIOSIS ANEMIA IRON DEFICIENCIES NEUROMUSCULAR SCOLIOSIS PERIOPERATIVE/POSTOPERATIVE COMPLICATIONS POSTOPERATIVE COGNITIVE DYSFUNCTION SPINAL FUSION

Contacts and locations

Locations

Columbia University Medical Center
RECRUITING

New York, New York, 10032, United States

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