Cerebral arterial disease

This study tests a device called the Surpass Evolve Flow Diverter, a small mesh tube placed inside an artery to redirect blood flow away from a brain aneurysm. The goal is to safely close the aneurysm and prevent it from rupturing. About 248 adults with unruptured, wide-neck aneu…

This study follows 246 people who received the Pipeline Shield device to treat brain aneurysms. The device is a small mesh tube that blocks blood flow to the aneurysm, reducing rupture risk. Researchers are checking how well the aneurysm seals, whether the artery narrows, and if …

This study looks at a device called ENTERPRISE 2 that helps doctors treat brain aneurysms (a bulging blood vessel in the brain). The device is used during a procedure to block the aneurysm with coils. The study includes 164 people aged 18 to 80 with certain types of brain aneurys…

This study tests a new coil device (Kaneka i-ED) in 50 people with wide-necked brain aneurysms. The coil is placed inside the aneurysm to block blood flow and prevent rupture. Researchers will check how well it works, how safe it is, and whether it saves money compared to standar…

This study tests a device called the Contour System to treat brain aneurysms (weak spots in blood vessels that can burst). The device is placed inside the aneurysm to block blood flow and prevent rupture. The trial involves 250 adults aged 18-75 with a specific type of aneurysm. …

This study follows 500 people who received the Surpass Evolve flow diverter, a device placed in brain arteries to treat aneurysms. Researchers will track safety and effectiveness for up to 5 years, focusing on stroke risk and aneurysm closure. The goal is to confirm the device wo…

This study is testing a new device called the Citadel Embolization Device, a coil used to block blood flow in brain aneurysms. It involves 150 adults aged 18-80 with unruptured or recently ruptured wide-neck aneurysms. The goal is to see if the device safely and effectively seals…

This study follows 195 adults who received the WEB device, a mesh implant used to block blood flow into wide-neck brain aneurysms. Researchers are checking how well the device works and its safety over one year. The goal is to confirm that the device remains a reliable option for…

This study is testing a device called FRED X, a small mesh tube placed inside an artery to block blood flow to a brain aneurysm. The goal is to see if it works as well as the earlier FRED device in preventing strokes and sealing the aneurysm. About 154 participants with a single …

This early study tests a new, experimental device called the HARBOR Occlusion Device for treating brain aneurysms. Ten adults with a single unruptured brain aneurysm will receive the device to see if it safely and effectively blocks blood flow to the aneurysm. The goal is to prev…

This study is testing a device called the Pipeline™ Flex Embolization Device with Shield Technology™ to treat wide-necked brain aneurysms. The device is a small mesh tube that is placed inside the artery to divert blood flow away from the aneurysm, helping it heal. The study will…

This study tests a new device called SEAL™ that is placed inside a brain aneurysm to block blood flow and prevent rupture. About 279 adults with unruptured or recently ruptured aneurysms are taking part. The goal is to see if the device safely and effectively seals the aneurysm w…

This study is checking whether the Accero stent is safe and works well for people with brain aneurysms. Researchers are following 130 patients who already received the stent as part of routine care. They will use imaging and disability scales to see how patients do over time.

This study tests a procedure that uses tiny coils to block blood flow in brain aneurysms (bulging blood vessels). The goal is to seal the aneurysm and prevent rupture. About 164 people with aneurysms 4-14mm in size are being followed for one year after treatment.

This study tests a drug-coated stent designed to block blood flow into unruptured brain aneurysms, helping them heal. Researchers will follow 280 patients for 12 months after the stent is placed, checking how well the aneurysm closes and watching for any complications. The goal i…

This study is testing the safety and effectiveness of a device called Silk Vista, used to treat brain aneurysms (a bulging blood vessel that can burst). Researchers are following 234 patients who already received the device as part of their normal care. The goal is to see how wel…

This study tests a new device called nOCT that acts like a tiny camera on a flexible wire. It slides into brain blood vessels during standard aneurysm treatment to take detailed pictures of the vessel wall and any implanted coils or stents. The goal is to see if these images help…

This study evaluates RDX-Aneurysm, a computer-assisted detection software designed to help radiologists find saccular intracranial aneurysms (bulging blood vessels in the brain) on MRI scans. Researchers will analyze 550 past scans—half with confirmed aneurysms and half without—t…

This study tests a laser-based imaging method that shows blood flow in the brain in real time during surgery. It involves 20 adults having brain surgery for conditions like aneurysms. The goal is to see if this technique can give surgeons continuous feedback, unlike the current d…

This study tests whether an AI program can find unruptured brain aneurysms on standard CT scans that people already get for other reasons. Ten adults with risk factors (like high blood pressure or being over 40) will have their scans checked by AI and then by a radiologist. The g…

This study tests a new exercise therapy called Progressive Abduction Loading Therapy for people who recently had a stroke. The goal is to reduce a common arm problem called 'flexion synergy' that makes it hard to reach outward. 86 participants will receive either the new therapy …

This study compares two physical therapy approaches—Rood's techniques (using touch, stretch, and ice) and PNF patterns (diagonal movements)—to improve arm and hand function in people who recently had a stroke. 28 adults aged 40-60 with a first-time stroke will receive one of the …

This study compares two physical therapy techniques—PNF and NDT—to see which better helps stroke survivors improve trunk control and balance. It will involve 32 people aged 40-65 who have had a recent stroke. Participants will receive electrical stimulation plus one of the two th…

This study is creating a statewide collection of blood samples and medical information from people with various brain blood vessel diseases, such as stroke and dementia. The goal is to build a resource that scientists can use in future research to better understand and potentiall…

This study looks at how social factors like income, education, and lifestyle might influence the risk of a brain aneurysm bursting. Researchers will analyze data from 1,800 patients using artificial intelligence to find patterns. The goal is to improve risk prediction and help pr…

This study looks at how often nurses should check on people in the ICU after they have had a brain aneurysm treated. The goal is to see if checking every hour versus every two hours affects how well patients sleep. Thirty adults who had a planned aneurysm coiling will take part, …

This study uses MRI scans to check for hidden brain aneurysms in close relatives (parents, siblings, or children) of people who have had a bleeding aneurysm. It aims to find who is at higher risk and how lifestyle factors like smoking or high blood pressure affect that risk. Abou…

This study tests a new computer-based visual training task for people who have lost part of their vision due to a stroke. Participants watch moving patterns on a screen and learn to detect motion direction, with the goal of improving visual abilities. The study first checks if th…

This study looks at whether platelet activation in the blood is higher in people whose brain aneurysm has already burst compared to those with an unruptured aneurysm. Researchers will collect blood samples from 230 patients during treatment. The goal is to see if platelet activit…

This study follows 400 people who had a brain aneurysm rupture and were treated with a procedure called embolization. The goal is to learn about their long-term recovery and whether the aneurysm can come back. Researchers will track neurological outcomes using a standard scale. T…

This study uses advanced MRI scans to measure blood flow in the brains of 100 adults with moyamoya disease, a condition that narrows major brain arteries and raises stroke risk. Participants will have scans and cognitive tests before and after their clinically needed surgery. The…

This study looks at how brain aneurysms (specifically intracranial dissecting aneurysms) change over time. Researchers are using high-resolution MRI scans and computer models to find patterns that might predict if an aneurysm will get worse. The goal is to build an AI tool that h…

This study looks at how the brain's visual system changes in the year after a stroke that damages the vision center. Researchers will measure vision and brain structure over time, and give participants a home-based computer training program that asks them to detect moving dots. T…

This study is a registry that will collect real-world data from 750 people with brain aneurysms treated with MicroVention devices. The goal is to see how well these devices work and how safe they are in everyday medical practice. Participants will be followed for at least one yea…

This study tests whether artificial intelligence can predict malignant brain edema, a life-threatening swelling, in patients who have had a major stroke. Researchers will analyze CT scans and clinical data from over 1,600 patients to see if the AI can identify early warning signs…