Brain aneurysm device under Long-Term scrutiny

NCT ID NCT04839705

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 195 adults who received the WEB device, a mesh implant used to block blood flow into wide-neck brain aneurysms. Researchers are checking how well the device works and its safety over one year. The goal is to confirm that the device remains a reliable option for treating these aneurysms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

WEB device (a mesh implant used to block blood flow into brain aneurysms)

What this could lead to

If successful, this study could confirm that the WEB device is a safe and effective long-term option for treating certain brain aneurysms, reducing the need for more invasive surgery.

What could go wrong

This is an observational follow-up study, not a new treatment test. The device is already approved, so the main risk is that long-term results may show lower effectiveness or higher complication rates than expected.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Aneurysm brain aneurysm cerebrovascular disorder intracranial arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Abbott Northwestern Hospital Allina Health

    Minneapolis, Minnesota, 55407, United States

  • Albany Medical Center

    Albany, New York, 12208, United States

  • Baptist Health Systems

    Lexington, Kentucky, 40503, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21287, United States

  • LSU Health Sciences Center at Shreveport

    Shreveport, Louisiana, 71103, United States

  • Massachusetts General Brigham Incorporated

    Boston, Massachusetts, 02114, United States

  • Memorial Health Systems

    Hollywood, Florida, 33021, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • Northshore University Hospital/Northwell Health

    Manhasset, New York, 11030, United States

  • Norton Healthcare

    Louisville, Kentucky, 40241, United States

  • Ohio State University

    Columbus, Ohio, 43210, United States

  • OhioHealth Research Institute

    Columbus, Ohio, 43214, United States

  • Orlando Health Neuroscience Institute

    Orlando, Florida, 32806, United States

  • SUNY Stony Brook

    Stony Brook, New York, 11794, United States

  • Semmes Murphey

    Memphis, Tennessee, 38120, United States

  • The Queen's Medical Center Neuroscience Institute

    Honolulu, Hawaii, 96813, United States

  • The Toledo Hospital d/b/a ProMedica Toledo Hospital

    Toledo, Ohio, 43606, United States

  • The Washington University

    St Louis, Missouri, 63110, United States

  • Thomas Jefferson University Hospital

    Philadelphia, Pennsylvania, 19107, United States

  • UMass Memorial Health

    Worcester, Massachusetts, 01655, United States

  • University of Buffalo

    Buffalo, New York, 14203, United States

  • University of Iowa Hospitals and Clinics

    Iowa City, Iowa, 52242, United States

  • University of Kansas Health System

    Kansas City, Kansas, 66160, United States

  • University of Kentucky, Department of Neurosurgery

    Lexington, Kentucky, 40536, United States

  • University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, 73104, United States

  • University of Pennsylvania Health Systems

    Philadelphia, Pennsylvania, 19104, United States

  • West Virginia University

    Morgantown, West Virginia, 26506, United States