New study tests mesh device to seal dangerous brain aneurysms

NCT ID NCT06411418

Ongoing Disease control Sponsor: Jacobs institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a device called the Pipeline™ Flex Embolization Device with Shield Technology™ to treat wide-necked brain aneurysms. The device is a small mesh tube that is placed inside the artery to divert blood flow away from the aneurysm, helping it heal. The study will follow 10 adults to see how safe the device is, focusing on whether any blood clots form. The device is already approved for use, so this study is collecting more real-world evidence.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Pipeline™ Flex Embolization Device with Shield Technology™ (a mesh tube placed inside the artery to divert blood flow away from the aneurysm)
What this could lead to: If successful, this could confirm that the device is a safe and effective option for treating wide-necked brain aneurysms, potentially reducing the need for more invasive surgery.
What could go wrong: This is a very small study (10 people) and is not randomized. It only looks at short-term safety (clotting events), not long-term outcomes. The device is already approved, so this is more about confirming real-world use than discovering something new.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

brain aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTRACRANIAL ANEURYSMS

Contacts and locations

Locations

University at Buffalo Neurosurgery

Buffalo, New York, 14203, United States

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Other studies related to the condition(s) this trial covers.